Cellosaurus OSC-20 (CVCL_3087)

Cell line name OSC-20
Synonyms OSC20
Accession CVCL_3087
Resource Identification Initiative To cite this cell line use: OSC-20 (RRID:CVCL_3087)
Comments Part of: COSMIC cell lines project.
Doubling time: 27.4 hours, at 35th passage (CelloPub=CLPUB00095).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Derived from metastatic site: Cervical lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP


Yokoi T., Hirata S., Nishimura F., Miyakawa A., Odajima T., Kohama G.-I., Mochizuki Y.
Some properties of a newly established human cell line from a oral squamous carcinoma.
Tumor Res. 25:93-103(1990)

Yonekura N., Yokosawa N., Hariya Y., Dehari H., Kohama G.-I., Fujii N.
Interferon-alpha and interferon-gamma augment apoptosis in oral carcinoma cells treated with Shiga toxin 2 (Stx2).
Tumor Res. 35:25-33(2000)

PubMed=19123955; DOI=10.1186/1479-5876-7-1
Kobayashi J.-I., Torigoe T., Hirohashi Y., Idenoue S., Miyazaki A., Yamaguchi A., Hiratsuka H., Sato N.
Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients.
J. Transl. Med. 7:1-1(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections JCRB; JCRB0197
Cell line databases/resources Cosmic-CLP; 1240196
GDSC; 1240196
Gene expression databases GEO; GSM827220
GEO; GSM1670309
Polymorphism and mutation databases Cosmic; 1120702
Cosmic; 1995604