Cellosaurus OSC-20 (CVCL_3087)

Cell line name OSC-20
Synonyms OSC20
Accession CVCL_3087
Resource Identification Initiative To cite this cell line use: OSC-20 (RRID:CVCL_3087)
Comments Doubling time: 27.4 hours, at 35th passage (CelloPub=CLPUB00095).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Derived from metastatic site: Cervical lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO12,13
D13S3178
D16S5399,13
D5S81813
D7S82010
TH019,9.3
TPOX8,11
vWA18
Publications

CLPUB00095
Yokoi T., Hirata S., Nishimura F., Miyakawa A., Odajima T., Kohama G.-I., Mochizuki Y.
Some properties of a newly established human cell line from a oral squamous carcinoma.
Tumor Res. 25:93-103(1990)

CLPUB00244
Yonekura N., Yokosawa N., Hariya Y., Dehari H., Kohama G.-I., Fujii N.
Interferon-alpha and interferon-gamma augment apoptosis in oral carcinoma cells treated with Shiga toxin 2 (Stx2).
Tumor Res. 35:25-33(2000)

PubMed=19123955; DOI=10.1186/1479-5876-7-1
Kobayashi J.-I., Torigoe T., Hirohashi Y., Idenoue S., Miyazaki A., Yamaguchi A., Hiratsuka H., Sato N.
Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients.
J. Transl. Med. 7:1-1(2009)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0197
Cell line databases/resources Cosmic-CLP; 1240196
GDSC; 1240196
LINCS_LDP; LCL-1220
Gene expression databases GEO; GSM827220
GEO; GSM1670309
Polymorphism and mutation databases Cosmic; 1120702
Cosmic; 1995604