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Cellosaurus OUMS-27 (CVCL_3090)

[Text version]

Cell line name OUMS-27
Synonyms OUMS27; Okayama University Medical School-27
Accession CVCL_3090
Resource Identification Initiative To cite this cell line use: OUMS-27 (RRID:CVCL_3090)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 41 hours (PubMed=9714054).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Has no IDH1 or IDH2 mutation (PubMed=22057234).
Heterozygous for TP53 p.Ser149fs and p.Pro153fs (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.16
Native American0
East Asian, North79.69
East Asian, South17.75
South Asian0
European, North0
European, South2.39
Disease Primary central chondrosarcoma (NCIt: C7155)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO10,12
D5S81810,11
D7S82010,12
D13S31712
D16S53914
TH019
TPOX11
vWA14

Run an STR similarity search on this cell line
Publications

DOI=10.11418/jtca1981.16.3_173
Mihara K., Miyazaki M., Fushimi K., Tsuji T., Inoue Y., Fukaya K.-I., Ohashi R., Namba M.
The p53 gene status and other cellular characteristics of human cell lines maintained in our laboratory.
Tissue Cult. Res. Commun. 16:173-178(1997)

PubMed=9359923; DOI=10.18926/AMO/30789
Mihara K., Miyazaki M., Kondo T., Fushimi K., Tsuji T., Inoue Y., Fukaya K.-I., Ishioka C., Namba M.
Yeast functional assay of the p53 gene status in human cell lines maintained in our laboratory.
Acta Med. Okayama 51:261-265(1997)

PubMed=9714054; DOI=10.1002/(SICI)1097-0215(19980911)77:6<854::AID-IJC10>3.0.CO;2-1
Kunisada T., Miyazaki M., Mihara K., Gao C., Kawai A., Inoue H., Namba M.
A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation.
Int. J. Cancer 77:854-859(1998)

PubMed=22057234; DOI=10.1038/ng.1004
Pansuriya T.C., van Eijk R., d'Adamo P., van Ruler M.A.J.H., Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G., Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L., Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N., Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M., Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Nat. Genet. 43:1256-1261(2011)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections JCRB; IFO50488
Cell line databases/resources CCLE; OUMS27_BONE
DepMap; ACH-001150
Lonza; 1500
Biological sample resources BioSample; SAMN03472799
BioSample; SAMN10987628
Gene expression databases GEO; GSM887480
GEO; GSM888561
Other Wikidata; Q54936776
Polymorphism and mutation databases Cosmic; 1602478
Cosmic; 1992325
IARC_TP53; 30137
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number19