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Cellosaurus OZ [Human cholangiocarcinoma] (CVCL_3118)

Cell line name OZ [Human cholangiocarcinoma]
Accession CVCL_3118
Resource Identification Initiative To cite this cell line use: OZ [Human cholangiocarcinoma] (RRID:CVCL_3118)
Comments Population: Japanese.
Doubling time: ~48 hours (CelloPub=CLPUB00469; PubMed=2889643).
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81813,14
D7S82010
D13S3178,12
D16S53910
TH016,9
TPOX9,11
vWA14,16

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Publications

CLPUB00469
Homma S.
Studies on the establishment and some biological characteristics of cultured human liver cancer cell lines. Their growth, functional and morphological characteristics and temperature sensitivities.
Jikeikai Med. J. 32:289-315(1985)

PubMed=2889643; DOI=10.1007/BF02773816
Homma S., Nagamori S., Fujise K., Yamazaki K., Hasumura S., Sujino H., Matsuura T., Shimizu K., Kameda H., Takaki K.
Human bile duct carcinoma cell line producing abundant mucin in vitro.
Gastroenterol. Jpn. 22:474-479(1987)

PubMed=21451941; DOI=10.1007/s00534-011-0376-7
Sato J., Kimura T., Saito T., Anazawa T., Kenjo A., Sato Y., Tsuchiya T., Gotoh M.
Gene expression analysis for predicting gemcitabine resistance in human cholangiocarcinoma.
J. Hepatobiliary Pancreat. Sci. 18:700-711(2011)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=26956050; DOI=10.18632/oncotarget.7914
Ding X.-W., Chaiteerakij R., Moser C.D., Shaleh H.M., Boakye J., Chen G., Ndzengue A., Li Y., Zhou Y.-L., Huang S.-B., Sinicrope F.A., Zou X.-P., Thomas M.B., Smith C.D., Roberts L.R.
Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells.
Oncotarget 7:20080-20092(2016)

PubMed=32899426; DOI=10.3390/cancers12092510
Scherer D., Davila Lopez M., Goeppert B., Abrahamsson S., Gonzalez Silos R., Nova I., Marcelain K., Roa J.C., Ibberson D., Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1032
JCRB; NIHS0282 - Discontinued
Biological sample resources BioSample; SAMN03472539
Encyclopedic resources Wikidata; Q54937185
Polymorphism and mutation databases Cosmic; 1122353
Cosmic; 1373552
Cosmic; 2629291
Cosmic; 2674046
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19