Cellosaurus logo
expasy logo

Cellosaurus PALL-2 (CVCL_3122)

[Text version]
Cell line name PALL-2
Synonyms PALL2; Ph1-positive Acute Lymphoblastic Leukemia-2
Accession CVCL_3122
Resource Identification Initiative To cite this cell line use: PALL-2 (RRID:CVCL_3122)
Comments Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=8428799; PubMed=10071072).
  • Mutation; HGNC; 12766; NSD2; Simple; p.His554Gln (c.1662C>G); ClinVar=VCV001680176; Zygosity=Heterozygous (PubMed=35124168).
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1345

Markers:
AmelogeninX,Y
CSF1PO10
D5S81811,12
D7S8208,11
D13S3178
D16S5399,10
TH017,9
TPOX8
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=8428799; DOI=10.1002/ijc.2910530318
Miyagi T., Ohyashiki J.H., Yamato K., Koeffler H.P., Miyoshi I.
Phenotypic and molecular analysis of Ph1-chromosome-positive acute lymphoblastic leukemia cell lines.
Int. J. Cancer 53:457-462(1993)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1345
JCRB; NIHS0546 - Discontinued
Cell line databases/resources SKIP; SKIP000748
Encyclopedic resources Wikidata; Q54937484
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number19