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Cellosaurus SKN (CVCL_3167)

Cell line name SKN
Accession CVCL_3167
Resource Identification Initiative To cite this cell line use: SKN (RRID:CVCL_3167)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 36 hours, at 29th passage (PubMed=556976).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Uterine corpus leiomyosarcoma (NCIt: C6340)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; RCB


Ishiwata I., Nozawa S., Nagai S., Kurihara S., Mikata A.
Establishment of a human leiomyosarcoma cell line.
Cancer Res. 37:658-664(1977)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections JCRB; IFO50314
JCRB; FDSC0031 - Discontinued
RCB; RCB0513
Cell line databases/resources CCLE; SKN_URINARY_TRACT
Cosmic-CLP; 1240215
GDSC; 1240215
Ontologies CLO; CLO_0050881
Biological sample resources BioSample; SAMN03470820
BioSample; SAMN03472277
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827211
GEO; GSM1670447
Other Wikidata; Q54954754
Polymorphism and mutation databases Cosmic; 1330908