ID   VL51
AC   CVCL_3169
SY   SLVL; VL-51
DR   CLO; CLO_0050869
DR   ArrayExpress; E-MTAB-3610
DR   BioSample; SAMN03472064
DR   cancercelllines; CVCL_3169
DR   Cell_Model_Passport; SIDM00374
DR   Cosmic-CLP; 1331032
DR   DepMap; ACH-002062
DR   EGA; EGAS00001000978
DR   GDSC; 1331032
DR   GEO; GSM827255
DR   GEO; GSM866167
DR   GEO; GSM1035345
DR   GEO; GSM1035346
DR   GEO; GSM1670458
DR   JCRB; JCRB0159
DR   JCRB; NIHS0247
DR   LINCS_LDP; LCL-1952
DR   PharmacoDB; SLVL_1427_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_3169
DR   RCB; RCB1702
DR   Wikidata; Q54993196
RX   PubMed=8551798;
RX   PubMed=20215515;
RX   PubMed=27397505;
RX   PubMed=29892436;
RX   PubMed=30894373;
RX   PubMed=35839778;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Population: Japanese.
CC   Doubling time: 70-80 hours (PubMed=8551798); ~28 hours (Note=Lot 11252016) (JCRB=JCRB0159).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Genome ancestry: African=0.61%; Native American=0.13%; East Asian, North=76.13%; East Asian, South=22.43%; South Asian=0.59%; European, North=0%; European, South=0.1% (PubMed=30894373).
CC   Discontinued: JCRB; NIHS0247; true.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): Cosmic-CLP; JCRB; RCB
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 8,10
ST   D16S539: 12
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   TH01: 8,9
ST   TPOX: 8
ST   vWA: 17,18
DI   NCIt; C4663; Splenic marginal zone lymphoma
DI   ORDO; Orphanet_86854; Splenic marginal zone lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   70Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 32
//
RX   PubMed=8551798; DOI=10.1016/0145-2126(95)00059-3;
RA   Inokuchi K., Abo J., Takahashi H., Miyake K., Inokuchi S., Dan K.,
RA   Nomura T.;
RT   "Establishment and characterization of a villous lymphoma cell line
RT   from splenic B-cell lymphoma.";
RL   Leuk. Res. 19:817-822(1995).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S.,
RA   Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P.,
RA   Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H.,
RA   Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=29892436; DOI=10.1098/rsos.172472;
RA   Shioda S., Kasai F., Watanabe K., Kawakami K., Ohtani A., Iemura M.,
RA   Ozawa M., Arakawa A., Hirayama N., Kawaguchi E., Tano T., Miyata S.,
RA   Satoh M., Shimizu N., Kohara A.;
RT   "Screening for 15 pathogenic viruses in human cell lines registered at
RT   the JCRB Cell Bank: characterization of in vitro human cells by viral
RT   infection.";
RL   R. Soc. Open Sci. 5:172472-172472(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010;
RA   Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N.,
RA   Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J.,
RA   Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L.,
RA   Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S.,
RA   Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B.,
RA   Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.;
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//