Cellosaurus cell line T.Tn (CVCL_3175)

• Mutation; HGNC; 11998; TP53; Simple; p.Val272Met (c.814G>A); ClinVar=VCV000185814; Zygosity=Unspecified (PubMed=9290701).
  

DOI=10.5794/jjoms.36.307
Takahashi K., Kanazama H., Chan C.-T., Hosono T., Takahara M., Sato K.-i.
A case of esophageal carcinoma metastatic to the mandible and characterization of two cell lines (T-T and T-Tn) established from the oral tumor.
Nihon Koku Geka Gakkai Zasshi 36:307-316(1990)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=15885884; DOI=10.1016/j.canlet.2005.03.036
Lo P.H.-Y., Leung A.C.-C., Xiong W.-J., Law S., Duh F.-M., Lerman M.I., Stanbridge E.J., Lung M.L.
Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-regulation of BLU in some esophageal squamous cell carcinomas.
Cancer Lett. 234:184-192(2006)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)