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Cellosaurus TMD5 (CVCL_3218)

[Text version]
Cell line name TMD5
Synonyms Tokyo Medical and Dental university 5
Accession CVCL_3218
Resource Identification Initiative To cite this cell line use: TMD5 (RRID:CVCL_3218)
Comments Population: Japanese.
Doubling time: 50 hours (PubMed=10071078).
Omics: Deep quantitative proteome analysis.
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: STR profile from personal communication of Leo I.R.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
STR profile Source(s): JCRB; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,13
D1S165611,18.3
D2S44110,12
D2S133817,19
D3S135815,17
D5S8189,13
D7S82010,11
D8S117910,14
D10S124812,16
D12S39118,24
D13S3178
D16S53910,12
D18S5114,15
D19S43312,14.2
D21S1130
D22S104511,17
DYS39110
FGA21,23
SE3322,29.2
TH019
TPOX8
vWA17,18

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Publications

PubMed=10071072; DOI=10.1016/s0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10071078; DOI=10.1016/S0145-2126(98)00172-6
Tohda S., Sakashita C., Fukuda T., Murakami N., Nara N.
Establishment of a double Philadelphia chromosome-positive acute lymphoblastic leukemia-derived cell line, TMD5: effects of cytokines and differentiation inducers on growth of the cells.
Leuk. Res. 23:255-261(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Cell line collections (Providers) JCRB; IFO50516
Biological sample resources BioSample; SAMN03472802
Encyclopedic resources Wikidata; Q54972692
Gene expression databases GEO; GSM5137748
GEO; GSM5137768
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number21