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Cellosaurus TYK-nu.CP-r (CVCL_3221)

Cell line name TYK-nu.CP-r
Synonyms TYK-nu (R); TYKNU CPR
Accession CVCL_3221
Resource Identification Initiative To cite this cell line use: TYK-nu.CP-r (RRID:CVCL_3221)
Comments Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Omics: Deep proteome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Caution: It is possible that TYK-nu.CP-r and TYK-nu-CisR (CVCL_EQ58) are the same cell line.
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1776 (TYK-nu)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): JCRB


Yoshiya N., Adachi S., Misawa Y., Yuzawa H., Honda T., Kanazawa K., Takeuchi S., Tanaka K., Tanaka K.
Isolation of cisplatin-resistant subline from human ovarian cancer cell line and analysis of its cell-biological characteristics.
Nihon Sanka Fujinka Gakkai Zasshi 41:7-14(1989)

PubMed=11330945; DOI=10.1006/gyno.2001.6132
Watanabe T., Imoto I., Kosugi Y., Ishiwata I., Inoue S., Takayama M., Sato A., Inazawa J.
A novel amplification at 17q21-23 in ovarian cancer cell lines detected by comparative genomic hybridization.
Gynecol. Oncol. 81:172-177(2001)

PubMed=12417041; DOI=10.1111/j.1349-7006.2002.tb01213.x
Watanabe T., Imoto I., Katahira T., Hirasawa A., Ishiwata I., Emi M., Takayama M., Sato A., Inazawa J.
Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers.
Jpn. J. Cancer Res. 93:1114-1122(2002)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27561551; DOI=10.1038/ncomms12645
Coscia F., Watters K.M., Curtis M., Eckert M.A., Chiang C.Y., Tyanova S., Montag A., Lastra R.R., Lengyel E., Mann M.
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Nat. Commun. 7:12645-12645(2016)

Cell line collections JCRB; JCRB0234.1
Cell line databases/resources CGH-DB; 383-2
CGH-DB; 9360-4
Ontologies EFO; EFO_0006767
Gene expression databases ArrayExpress; E-MTAB-2706
Other Wikidata; Q54973462