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Cellosaurus XP2OS(SV) (CVCL_3242)

[Text version]
Cell line name XP2OS(SV)
Synonyms XP2OS (SV); XP2OS-SV; XP20S-SV40; XP20s(SV40)
Accession CVCL_3242
Resource Identification Initiative To cite this cell line use: XP2OS(SV) (RRID:CVCL_3242)
Comments Population: Japanese.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Caution: Could be identical to GM04312 (Cellosaurus=CVCL_ZN80).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 12814; XPA; Simple; c.390-1G>C (IVS3-1G>C); ClinVar=VCV000264684; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
Disease Xeroderma pigmentosum, complementation group A (NCIt: C3965)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F510 (XP2OS)
Children:
CVCL_ZR65 (XP2OS(SV)neo)
Sex of cell Female
Age at sampling 7Y
Category Transformed cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO10,11
D5S81811
D7S8208,12
D13S3179
D16S53912
TH019
TPOX11
vWA14,16

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Publications

PubMed=7000335; DOI=10.1016/0304-3835(80)90072-5
Ishizaki K., Yagi T., Takebe H.
Cytotoxic effects of protease inhibitors on human cells. 1. High sensitivity of xeroderma pigmentosum cells to antipain.
Cancer Lett. 10:199-205(1980)

PubMed=2039995
Yagi T., Tatsumi-Miyajima J., Sato M., Kraemer K.H., Takebe H.
Analysis of point mutations in an ultraviolet-irradiated shuttle vector plasmid propagated in cells from Japanese xeroderma pigmentosum patients in complementation groups A and F.
Cancer Res. 51:3177-3182(1991)

Cross-references
Cell line collections (Providers) JCRB; JCRB0301
JCRB; KURB1008
Encyclopedic resources Wikidata; Q54994913
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19