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Cellosaurus XR-V15B (CVCL_3271)

[Text version]
Cell line name XR-V15B
Synonyms GM16144
Accession CVCL_3271
Resource Identification Initiative To cite this cell line use: XR-V15B (RRID:CVCL_3271)
Comments Transformant: ChEBI; CHEBI:23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; Q60449; Xrcc5; Simple; p.Ala372_Glu417del46 (c.1114_1251del138); Zygosity=Unspecified (PubMed=8657125).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_6296 (V79B)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=2460764; DOI=10.1016/0167-8817(88)90025-9
Zdzienicka M.Z., Tran Q., van der Schans G.P., Simons J.W.I.M.
Characterization of an X-ray-hypersensitive mutant of V79 Chinese hamster cells.
Mutat. Res. 194:239-249(1988)

PubMed=8657125; DOI=10.1128/mcb.16.4.1519
Errami A., Smider V., Rathmell W.K., He D.-M., Hendrickson E.A., Zdzienicka M.Z., Chu G.
Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants.
Mol. Cell. Biol. 16:1519-1526(1996)

Cross-references
Cell line collections (Providers) ATCC; CRL-2349
Coriell; GM16144
RCB; RCB2339
Cell line databases/resources CLO; CLO_0009694
CLO; CLO_0018891
CLO; CLO_0051580
Encyclopedic resources Wikidata; Q54995044
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number15