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Cellosaurus HCC1937 BL (CVCL_3281)

[Text version]

Cell line name HCC1937 BL
Synonyms HCC1937-BL; HCC-1937BL; HCC1937BL
Accession CVCL_3281
Resource Identification Initiative To cite this cell line use: HCC1937 BL (RRID:CVCL_3281)
Comments Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Misspelling: HCC2337; In PubMed=22032724, probably due to confusion with ATCC catalog number (CRL-2337).
Misspelling: HCC-2337; In PubMed=25960936, probably due to confusion with ATCC catalog number (CRL-2337).
Sequence variations Heterozygous for BRCA1 p.Gln1756Profs*74 (c.5266dupC) (5382insC). The breast carcinoma cell line HCC1937 (CVCL_0290) is homozygous for the same mutation (PubMed=9699648; PubMed=22032724).
HLA typing Source: PubMed=25960936
Class I
Class II
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0290 ! HCC1937
Sex of cell Female
Age at sampling 24Y
Category Transformed cell line
STR profile Source(s): ATCC


Run an STR similarity search on this cell line

Tomlinson G.E., Chen T.T.-L., Stastny V.A., Virmani A.K., Spillman M.A., Tonk V., Blum J.L., Schneider N.R., Wistuba I.I., Shay J.W., Minna J.D., Gazdar A.F.
Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.
Cancer Res. 58:3237-3242(1998)

PubMed=9833771; DOI=10.1002/(SICI)1097-0215(19981209)78:6<766::AID-IJC15>3.0.CO;2-L
Gazdar A.F., Kurvari V., Virmani A.K., Gollahon L., Sakaguchi M., Westerfield M., Kodagoda D., Stasny V., Cunningham H.T., Wistuba I.I., Tomlinson G.E., Tonk V., Ashfaq R., Leitch A.M., Minna J.D., Shay J.W.
Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.
Int. J. Cancer 78:766-774(1998)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=22032724; DOI=10.1186/1755-8794-4-75
Ha K.C.H., Lalonde E., Li L., Cavallone L., Natrajan R., Lambros M.B., Mitsopoulos C., Hakas J., Kozarewa I., Fenwick K., Lord C.J., Ashworth A., Vincent-Salomon A., Basik M., Reis-Filho J.S., Majewski J., Foulkes W.D.
Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines.
BMC Med. Genomics 4:75-75(2011)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

Cell line collections ATCC; CRL-2337
KCLB; 9S1937BL
Cell line databases/resources Cell_Model_Passport; SIDM00873
DepMap; ACH-002375
Ontologies CLO; CLO_0003646
Biological sample resources BioSample; SAMN03471821
Other Wikidata; Q28872486
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number17