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Cellosaurus Lu-140 (CVCL_3335)

[Text version]
Cell line name Lu-140
Synonyms NCC-c-Lu-140; LU-140
Accession CVCL_3335
Resource Identification Initiative To cite this cell line use: Lu-140 (RRID:CVCL_3335)
Comments Population: Japanese.
Doubling time: 144 hours (PubMed=3022030).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg342Glnfs*3 (c.1025delG); Zygosity=Unspecified (PubMed=1312700; PubMed=10536175).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX
CSF1PO12
D5S8189
D7S8209,10
D13S31711
D16S53910
TH017
TPOX11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=3022030; DOI=10.1093/oxfordjournals.jjco.a039144
Terasaki T., Shimosato Y., Nakajima T., Tsumuraya M., Morinaga S., Hirohashi S., Yamaguchi K., Kato K., Ichinose H., Nagatsu T.
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn. J. Clin. Oncol. 16:203-212(1986)

PubMed=1312700
Sameshima Y., Matsuno Y., Hirohashi S., Shimosato Y., Mizoguchi H., Sugimura T., Terada M., Yokota J.
Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small-cell lung carcinoma.
Oncogene 7:451-457(1992)

PubMed=10536175; DOI=10.3892/ijo.15.5.927
Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.
Int. J. Oncol. 15:927-934(1999)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7
Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T., Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S., Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

Cross-references
Cell line collections (Providers) RCB; RCB0470
Cell line databases/resources CLO; CLO_0050032
CGH-DB; 101-1
CGH-DB; 9064-4
Biological sample resources BioSample; SAMN03472319
Encyclopedic resources Wikidata; Q54903201
Polymorphism and mutation databases Cosmic; 801608
Cosmic; 809124
Cosmic; 918008
Cosmic; 1212196
Cosmic; 1571752
IARC_TP53; 1018
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number20