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Cellosaurus Lu-143 (CVCL_3348)

[Text version]
Cell line name Lu-143
Accession CVCL_3348
Resource Identification Initiative To cite this cell line use: Lu-143 (RRID:CVCL_3348)
Comments Population: Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; c.782+1G>T; ClinVar=VCV000496048; Zygosity=Unspecified; Note=Splice donor mutation (PubMed=1312700).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811
D7S82010,11
D13S3178
D16S5399
TH016
TPOX11
vWA17,20

Run an STR similarity search on this cell line
Publications

PubMed=1312700
Sameshima Y., Matsuno Y., Hirohashi S., Shimosato Y., Mizoguchi H., Sugimura T., Terada M., Yokota J.
Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small-cell lung carcinoma.
Oncogene 7:451-457(1992)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7
Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T., Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S., Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

Cross-references
Cell line collections (Providers) RCB; RCB1773
Cell line databases/resources CLO; CLO_0050036
cancercelllines; CVCL_3348
CGH-DB; 102-1
CGH-DB; 9066-4
Biological sample resources BioSample; SAMN03472076
Encyclopedic resources Wikidata; Q54903203
Polymorphism and mutation databases Cosmic; 809126
IARC_TP53; 1020
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19