ID   Lu-24
AC   CVCL_3349
SY   NCC-c-Lu-24; LU-24; Lu24
DR   CLO; CLO_0050035
DR   BioSample; SAMN03472074
DR   CGH-DB; 98-1
DR   CGH-DB; 9057-4
DR   Cosmic; 801603
DR   Cosmic; 809117
DR   Cosmic; 844893
DR   Cosmic; 876159
DR   Cosmic; 918003
DR   Cosmic; 1239928
DR   Cosmic; 2125269
DR   Cosmic; 2668336
DR   IARC_TP53; 28448
DR   RCB; RCB1771
DR   Wikidata; Q54903205
RX   DOI=10.5795/jjscc.24.451;
RX   PubMed=1312700;
RX   PubMed=3022030;
RX   PubMed=10536175;
RX   PubMed=11005564;
RX   PubMed=12107105;
RX   PubMed=19472407;
RX   PubMed=20557307;
RX   PubMed=23716474;
CC   Population: Japanese.
CC   Doubling time: 102 hours (PubMed=3022030).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=1312700; PubMed=10536175; PubMed=20557307).
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
ST   Source(s): RCB
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9
ST   D16S539: 10
ST   D5S818: 9
ST   D7S820: 12
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 14,18
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   42Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 24
//
RX   DOI=10.5795/jjscc.24.451;
RA   Tsumuraya M., Nakajima T., Terasaki T., Kodama T., Shimosato Y.,
RA   Higuchi H., Uei Y.;
RT   "Analysis of LDH isoenzyme patterns in cell lines of the small cell
RT   carcinoma (lung) and retinoblastoma.";
RL   Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985).
//
RX   PubMed=1312700;
RA   Sameshima Y., Matsuno Y., Hirohashi S., Shimosato Y., Mizoguchi H.,
RA   Sugimura T., Terada M., Yokota J.;
RT   "Alterations of the p53 gene are common and critical events for the
RT   maintenance of malignant phenotypes in small-cell lung carcinoma.";
RL   Oncogene 7:451-457(1992).
//
RX   PubMed=3022030; DOI=10.1093/oxfordjournals.jjco.a039144;
RA   Terasaki T., Shimosato Y., Nakajima T., Tsumuraya M., Morinaga S.,
RA   Hirohashi S., Yamaguchi K., Kato K., Ichinose H., Nagatsu T.;
RT   "Changes in cell characteristics due to culture conditions in cell
RT   lines from human small cell lung cancer.";
RL   Jpn. J. Clin. Oncol. 16:203-212(1986).
//
RX   PubMed=10536175; DOI=10.3892/ijo.15.5.927;
RA   Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.;
RT   "Comprehensive analysis of p53 gene mutation characteristics in lung
RT   carcinoma with special reference to histological subtypes.";
RL   Int. J. Oncol. 15:927-934(1999).
//
RX   PubMed=11005564; DOI=10.1038/sj.neo.7900094;
RA   Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M.,
RA   Yokota J.;
RT   "Mutation and expression of the DCC gene in human lung cancer.";
RL   Neoplasia 2:300-305(2000).
//
RX   PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7;
RA   Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T.,
RA   Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S.,
RA   Inazawa J.;
RT   "A novel target gene, SKP2, within the 5p13 amplicon that is
RT   frequently detected in small cell lung cancers.";
RL   Am. J. Pathol. 161:207-216(2002).
//
RX   PubMed=19472407; DOI=10.1002/humu.21028;
RA   Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R.,
RA   Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.;
RT   "A gene-alteration profile of human lung cancer cell lines.";
RL   Hum. Mutat. 30:1199-1206(2009).
//
RX   PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x;
RA   Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.;
RT   "Prevalence of human papillomavirus 16/18/33 infection and p53
RT   mutation in lung adenocarcinoma.";
RL   Cancer Sci. 101:1891-1896(2010).
//
RX   PubMed=23716474; DOI=10.1002/gcc.22076;
RA   Iwakawa R., Takenaka M., Kohno T., Shimada Y., Totoki Y., Shibata T.,
RA   Tsuta K., Nishikawa R., Noguchi M., Sato-Otsubo A., Ogawa S.,
RA   Yokota J.;
RT   "Genome-wide identification of genes with amplification and/or fusion
RT   in small cell lung cancer.";
RL   Genes Chromosomes Cancer 52:802-816(2013).
//