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Cellosaurus HCC1007 (CVCL_3374)

Cell line name HCC1007
Synonyms HCC-1007; Hamon Cancer Center 1007
Accession CVCL_3374
Resource Identification Initiative To cite this cell line use: HCC1007 (RRID:CVCL_3374)
Comments Part of: GrayJW breast cancer cell line panel.
Population: African American.
Omics: CNV analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Asp281His (c.841G>C); ClinVar=VCV000376588; Zygosity=Unspecified (PubMed=9865903).
Disease Breast ductal carcinoma (NCIt: C4017)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_3282 ! HCC1007 BL
CVCL_1244 ! HCC1008
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): ATCC; KCLB

Markers:
AmelogeninX
CSF1PO12,13
D3S135816
D5S81813
D7S82010
D13S31712
D16S53914,15
FGA23
TH017
TPOX6,11
vWA16,19 (KCLB)
19 (ATCC)

Run an STR similarity search on this cell line
Web pages https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
Publications

PubMed=9833771; DOI=10.1002/(SICI)1097-0215(19981209)78:6<766::AID-IJC15>3.0.CO;2-L
Gazdar A.F., Kurvari V., Virmani A.K., Gollahon L., Sakaguchi M., Westerfield M., Kodagoda D.R., Stasny V., Cunningham H.T., Wistuba I.I., Tomlinson G.E., Tonk V., Ashfaq R., Leitch A.M., Minna J.D., Shay J.W.
Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.
Int. J. Cancer 78:766-774(1998)

PubMed=9865903
Wistuba I.I., Behrens C., Milchgrub S., Syed S., Ahmadian M., Virmani A.K., Kurvari V., Cunningham T.H., Ashfaq R., Minna J.D., Gazdar A.F.
Comparison of features of human breast cancer cell lines and their corresponding tumors.
Clin. Cancer Res. 4:2931-2938(1998)

PubMed=11314036; DOI=10.1038/sj.onc.1204211
Forgacs E., Wren J.D., Kamibayashi C., Kondo M., Xu X.L., Markowitz S.D., Tomlinson G.E., Muller C.Y., Gazdar A.F., Garner H.R., Minna J.D.
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
Oncogene 20:1005-1009(2001)

PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008
Neve R.M., Chin K., Fridlyand J., Yeh J., Baehner F.L., Fevr T., Clark L., Bayani N., Coppe J.-P., Tong F., Speed T., Spellman P.T., DeVries S., Lapuk A., Wang N.J., Kuo W.-L., Stilwell J.L., Pinkel D., Albertson D.G., Waldman F.M., McCormick F., Dickson R.B., Johnson M.D., Lippman M.E., Ethier S.P., Gazdar A.F., Gray J.W.
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.
Cancer Cell 10:515-527(2006)

PubMed=19582160; DOI=10.1371/journal.pone.0006146
Kao J., Salari K., Bocanegra M., Choi Y.-L., Girard L., Gandhi J., Kwei K.A., Hernandez-Boussard T., Wang P., Gazdar A.F., Minna J.D., Pollack J.R.
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.
PLoS ONE 4:E6146-E6146(2009)

PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020
Timmerman L.A., Holton T., Yuneva M., Louie R.J., Padro M., Daemen A., Hu M., Chan D.A., Ethier S.P., van 't Veer L.J., Polyak K., McCormick F., Gray J.W.
Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.
Cancer Cell 24:450-465(2013)

Cross-references
Cell line collections (Providers) ATCC; CRL-2318 - Discontinued
KCLB; 9S1007
Cell line databases/resources cancercelllines; CVCL_3374
Biological sample resources BioSample; SAMN03471869
Encyclopedic resources Wikidata; Q54881517
Experimental variables resources EFO; EFO_0001168
Gene expression databases GEO; GSM350518
Polymorphism and mutation databases IARC_TP53; 10270
Progenetix; CVCL_3374
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number27