Home  |  Contact

Cellosaurus KE-39 (CVCL_3385)

[Text version]

Cell line name KE-39
Synonyms KE39
Accession CVCL_3385
Resource Identification Initiative To cite this cell line use: KE-39 (RRID:CVCL_3385)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~38.4 hours (PubMed=7599112).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.5
Native American0
East Asian, North89.52
East Asian, South4.53
South Asian0
European, North0
European, South4.45
Disease Gastric adenocarcinoma (NCIt: C4004)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 77Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200; RCB

Markers:
AmelogeninX
CSF1PO13
D2S133822
D3S135817
D5S81810
D7S82011
D8S117911,16
D13S3178,10
D16S53911
D18S5114,15
D19S43314.2,16.2
D21S1130
FGA22,23
Penta D11
Penta E18,23
TH017 (PubMed=25877200)
7,9.3 (RCB)
TPOX9,11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=7599112
Uesugi H., Yamashita K., Atari E., Shinoda H., Nishiyama T., Okayasu I., Yasuda S.
Establishment and characterization of strain KE-39 derived from human gastric cancer.
Hum. Cell 7:227-232(1994)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24807215; DOI=10.1038/ncomms4830
Liu J., McCleland M., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H., Wan Y., Chopra V., Yaylaoglu M.B., Yuan W., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830-3830(2014)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections RCB; RCB1434
Cell line databases/resources CCLE; KE39_STOMACH
Cell_Model_Passport; SIDM01582
DepMap; ACH-000507
Ontologies CLO; CLO_0050802
Biological sample resources BioSample; SAMN03470990
BioSample; SAMN03472139
BioSample; SAMN10987859
Chemistry resources PharmacoDB; KE39_741_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887204
GEO; GSM888277
Other Wikidata; Q54899716
Polymorphism and mutation databases Cosmic; 1187280
LiGeA; CCLE_164
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number16