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Cellosaurus KE-97 (CVCL_3386)

[Text version]

Cell line name KE-97
Synonyms KE97
Accession CVCL_3386
Resource Identification Initiative To cite this cell line use: KE-97 (RRID:CVCL_3386)
Comments Problematic cell line: Misidentified. Originally thought to be a mucinous gastric adenocarcinoma cell line from a 52 year old male patient but is a B-lymphoblastoid cell line (DSMZ; PubMed=30285677).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~28.8 hours (PubMed=7861622).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North80.49
East Asian, South19.51
South Asian0
European, North0
European, South0
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Transformed cell line
STR profile Source(s): PubMed=25877200; RCB

Markers:
AmelogeninX
CSF1PO10,12
D2S133820
D3S135815
D5S81811,13
D7S8208,12
D8S117910,15
D13S3178
D16S53911
D18S5116,17
D19S43312,14
D21S1131,32.2
FGA18,24
Penta D9,13
Penta E5
TH017,9
TPOX9,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=7861622; DOI=10.11405/nisshoshi1964.92.19
Uesugi H., Atari E.
Establishment and pathological study of a new poorly differentiated mucinous gastric cancer cell line.
Nihon Shokakibyo Gakkai Zasshi 92:19-25(1995)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24807215; DOI=10.1038/ncomms4830
Liu J., McCleland M., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H., Wan Y., Chopra V., Yaylaoglu M.B., Yuan W., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830-3830(2014)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940-940(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections RCB; RCB1435
Cell line databases/resources CCLE; KE97_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM01589
DepMap; ACH-000167
Ontologies CLO; CLO_0050806
Biological sample resources BioSample; SAMN03470997
BioSample; SAMN10987861
Chemistry resources PharmacoDB; KE97_742_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887205
GEO; GSM888278
Other Wikidata; Q54899720
Polymorphism and mutation databases Cosmic; 1187281
LiGeA; CCLE_884
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number18