ID   Lec1
AC   CVCL_3440
SY   CHO-Lec1; CHO Lec1; Pro-Lec1.3C; Pro-5 Lec1.3c; Pro-5WgaRI3C
DR   CLO; CLO_0007301
DR   ATCC; CRL-1735
DR   CCRID; 3101HAMGNHa8
DR   CLS; 305010
DR   Wikidata; Q54902418
RX   PubMed=1182798;
RX   PubMed=3785164;
RX   PubMed=6623313;
RX   PubMed=8910379;
RX   PubMed=24078077;
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-202.html
CC   Sequence variation: Mutation; UniProtKB; Q924C0; Mgat1; Simple; p.Gln339Arg; Zygosity=Unspecified (PubMed=8910379).
CC   Sequence variation: Mutation; UniProtKB; Q924C0; Mgat1; Simple; p.Lys401Arg; Zygosity=Unspecified (PubMed=8910379).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4382 ! CHO Pro-5
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 19
//
RX   PubMed=1182798; DOI=10.1016/0092-8674(75)90002-1;
RA   Stanley P., Caillibot V., Siminovitch L.;
RT   "Selection and characterization of eight phenotypically distinct lines
RT   of lectin-resistant Chinese hamster ovary cell.";
RL   Cell 6:121-128(1975).
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RX   PubMed=3785164; DOI=10.1128/mcb.6.4.1268-1275.1986;
RA   Ripka J., Shin S.-I., Stanley P.;
RT   "Decreased tumorigenicity correlates with expression of altered cell
RT   surface carbohydrates in Lec9 CHO cells.";
RL   Mol. Cell. Biol. 6:1268-1275(1986).
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RX   PubMed=6623313; DOI=10.1007/BF01574260;
RA   Stanley P.;
RT   "Lectin-resistant CHO cells: selection of new mutant phenotypes.";
RL   Somatic Cell Genet. 9:593-608(1983).
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RX   PubMed=8910379; DOI=10.1074/jbc.271.44.27818;
RA   Puthalakath H., Burke J., Gleeson P.A.;
RT   "Glycosylation defect in Lec1 Chinese hamster ovary mutant is due to a
RT   point mutation in N-acetylglucosaminyltransferase I gene.";
RL   J. Biol. Chem. 271:27818-27822(1996).
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RX   PubMed=24078077; DOI=10.1007/s00418-013-1146-1;
RA   Dong Z.-Z., Zuber C., Pierce M., Stanley P., Roth J.;
RT   "Reduction in Golgi apparatus dimension in the absence of a
RT   residential protein, N-acetylglucosaminyltransferase V.";
RL   Histochem. Cell Biol. 141:153-164(2014).
//