ID   143.98.2
AC   CVCL_3476
DR   CLO; CLO_0001085
DR   cancercelllines; CVCL_3476
DR   Wikidata; Q54581811
RX   Patent=US5543297;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11226.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 10,13
ST   D5S818: 13
ST   D7S820: 11,12
ST   TH01: 6
ST   TPOX: 11
ST   vWA: 18
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2270 ! 143B
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
//
RX   Patent=US5543297;
RA   Cromlish W.A., Kennedy B.P., O'Neill G., Vickers P.J., Wong E.,
RA   Mancini J.A.;
RT   "Human cyclooxygenase-2 cDNA and assays for evaluating cyclooxygenase-2
RT   activity.";
RL   Patent number US5543297, 06-Aug-1996.
//