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Cellosaurus 143B pML BK TK (CVCL_3477)

[Text version]

Cell line name 143B pML BK TK
Synonyms 143B PML BK TK
Accession CVCL_3477
Resource Identification Initiative To cite this cell line use: 143B pML BK TK (RRID:CVCL_3477)
Sequence variations Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2270 (143B)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO12
D5S81813
D7S82011,12
D13S31712
D16S53910,13
TH016
TPOX11
vWA18

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Publications

Patent=US4562155
Ricciardi R.P., Barbanti-Brodano G., Milanesi G.
Hybrid viral plasmid and microorganisms containing same.
Patent number US4562155, 31-Dec-1985

Cross-references
Cell line collections ATCC; CRL-8304
Cell line databases/resources LINCS_LDP; LCL-1418
Ontologies CLO; CLO_0001089
Other Wikidata; Q54581908
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number19