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Cellosaurus 1A2 (CVCL_3480)

[Text version]
Cell line name 1A2
Accession CVCL_3480
Resource Identification Initiative To cite this cell line use: 1A2 (RRID:CVCL_3480)
Comments Group: Patented cell line.
Problematic cell line: Misclassified. Parent cell line (GM01500) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8119.
Population: Caucasian.
Characteristics: Secretes IgG2 kappa.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Omics: SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D870 (GM01500)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81810,12
D7S82010
D13S31712
D16S53911
TH019,9.3
TPOX8
vWA16,19

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Publications

Patent=US4834975
Siadak A.W., Lostrom M.E.
Human monoclonal antibodies to serotypic lipopolysaccharide determinants on Gram-negative bacteria and their production.
Patent number US4834975, 30-May-1989

Patent=US5662905
Siadak A.W., Rosok M.J.
Monoclonal antibody compositions cross-reactive and cross-protective against P. aeruginosa serotypes.
Patent number US5662905, 02-Sep-1997

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-8119
ECACC; 93031502 - Discontinued
Cell line databases/resources CLO; CLO_0001146
IGRhCellID; 1A2
Biological sample resources BioSample; SAMN03471192
Encyclopedic resources Wikidata; Q54582644
Experimental variables resources EFO; EFO_0002094
Gene expression databases ArrayExpress; E-MTAB-38
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number24