ID   H9/HTLV-IIIB
AC   CVCL_3514
SY   H9/HTLV-IIIB NIH 1983
DR   CLO; CLO_0003613
DR   ATCC; CRL-8543
DR   cancercelllines; CVCL_3514
DR   HIVReagentProgram; ARP-400
DR   Wikidata; Q54872246
RX   Patent=US4520113;
RX   PubMed=2567177;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8543.
CC   Population: Caucasian.
CC   Virology: In vitro infected by HIV-1.
CC   Sequence variation: Gene deletion; HGNC; 7208; MPDZ; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): ATCC
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 8,12
ST   D16S539: 11,12
ST   D5S818: 11
ST   D7S820: 8,11
ST   TH01: 8,9
ST   TPOX: 8,9
ST   vWA: 14,15
DI   NCIt; C3366; Sezary syndrome
DI   ORDO; Orphanet_3162; Sezary syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1240 ! H9
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
//
RX   Patent=US4520113;
RA   Gallo R.C., Popovic M., Sarngadharan M.G.;
RT   "Serological detection of antibodies to HTLV-III in sera of patients
RT   with AIDS and pre-AIDS conditions.";
RL   Patent number US4520113, 28-May-1985.
//
RX   PubMed=2567177; DOI=10.1089/aid.1989.5.253;
RA   Mann D.L., O'Brien S.J., Gilbert D.A., Reid Y.A., Popovic M.,
RA   Read-Connole E.L., Gallo R.C., Gazdar A.F.;
RT   "Origin of the HIV-susceptible human CD4+ cell line H9.";
RL   AIDS Res. Hum. Retroviruses 5:253-255(1989).
//