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Cellosaurus RIN-m (CVCL_3584)

[Text version]

Cell line name RIN-m
Synonyms RINm
Accession CVCL_3584
Resource Identification Initiative To cite this cell line use: RIN-m (RRID:CVCL_3584)
Comments Characteristics: Established from the transplantable insulinoma RIN.
Characteristics: Secretes insulin and somatostatin (PubMed=6106192; PubMed=6141566).
Transformant: NCIt; C17262; X-Ray.
Derived from sampling site: Pancreas; islets of Langerhans.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH.
Hierarchy Children:
CVCL_3583 (RIN-14B)CVCL_0501 (RIN-m5F)
Originate from same individual CVCL_0352 ! INS-1
CVCL_J993 ! INS-2
CVCL_D163 ! RIN-r
Sex of cell Male
Age at sampling 666D
Category Cancer cell line

PubMed=6106192; DOI=10.1073/pnas.77.6.3519
Gazdar A.F., Chick W.L., Oie H.K., Sims H.L., King D.L., Weir G.C., Lauris V.
Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.
Proc. Natl. Acad. Sci. U.S.A. 77:3519-3523(1980)

PubMed=6295859; DOI=10.2337/diab.31.6.521
Bhathena S.J., Oie H.K., Gazdar A.F., Voyles N.R., Wilkins S.D., Recant L.
Insulin, glucagon, and somatostatin receptors on cultured cells and clones from rat islet cell tumor.
Diabetes 31:521-531(1982)

PubMed=6129963; DOI=10.1210/endo-112-3-1070
Oie H.K., Gazdar A.F., Minna J.D., Weir G.C., Baylin S.B.
Clonal analysis of insulin and somatostatin secretion and L-dopa decarboxylase expression by a rat islet cell tumor.
Endocrinology 112:1070-1075(1983)

PubMed=6141566; DOI=10.3181/00379727-175-41762
Bhathena S.J., Awoke S., Voyles N.R., Wilkins S.D., Recant L., Oie H.K., Gazdar A.F.
Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones.
Proc. Soc. Exp. Biol. Med. 175:35-38(1984)

Poitout V., Olson L.K., Robertson R.P.
Insulin-secreting cell lines: classification, characteristics and potential applications.
Diabetes Metab. 22:7-14(1996)

PubMed=8806089; DOI=10.1002/jcb.240630502
Gazdar A.F., Minna J.D.
NCI series of cell lines: an historical perspective.
J. Cell. Biochem. 63 Suppl. 24:1-11(1996)

PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

Cell line collections ATCC; CRL-2057
ECACC; 95071701
Cell line databases/resources CLDB; cl4151
Ontologies CLO; CLO_0008818
Other Wikidata; Q54950480
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number12