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Cellosaurus SW579 (CVCL_3603)

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Cell line name SW579
Synonyms SW-579; SW 579
Accession CVCL_3603
Resource Identification Initiative To cite this cell line use: SW579 (RRID:CVCL_3603)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: KuDOS 95 cell line panel.
From: Scott and White Clinic; Temple; USA.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations TERT c.228C>T (-124C>T); in promoter (PubMed=31068700).
Homozygous for TP53 p.Ile255Ser (c.764T>G) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.11
Native American1.95
East Asian, North0.43
East Asian, South0
South Asian0.91
European, North63.94
European, South32.66
Disease Thyroid gland squamous cell carcinoma (NCIt: C46008)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_1120 (CGTH-W-1)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): ATCC; CCRID; CLS

Markers:
AmelogeninX
CSF1PO13
D2S133817,18
D3S135815,18
D5S81811
D7S8208,9
D8S117911,13
D13S31713
D16S53911
D18S5115,17,18
D19S43313,14
D21S1129,31
FGA21,24
Penta D9,12
Penta E11,12
TH018,9.3
TPOX8,10
vWA14,18

Run an STR similarity search on this cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=264
http://www.cellresource.cn/fdetail.aspx?id=693
Publications

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections ATCC; HTB-107
BCRC; 60412
CLS; 300346/p467_SW-579
IZSLER; BS TCL 121
KCB; KCB 201304YJ
Cell line databases/resources CCLE; SW579_THYROID
CCRID; 3111C0001CCC000264
CCRID; 3131C0001000700125
Cell_Model_Passport; SIDM01167
DepMap; ACH-000163
IGRhCellID; SW579
Ontologies CLO; CLO_0009220
Biological sample resources BioSample; SAMN10988339
Chemistry resources PharmacoDB; SW579_1540_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887676
GEO; GSM888768
GEO; GSM1374931
GEO; GSM1374932
Other Wikidata; Q54971179
Polymorphism and mutation databases Cosmic; 1005454
Cosmic; 1006467
Cosmic; 1017791
Cosmic; 1041672
Cosmic; 1094773
Cosmic; 1339924
IARC_TP53; 1308
LiGeA; CCLE_771
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22