ID   WEHI-3
AC   CVCL_3622
SY   Wehi-3; WEHI 3; WEHI3
DR   BTO; BTO:0000295
DR   CLO; CLO_0009579
DR   CLO; CLO_0051420
DR   CLDB; cl4691
DR   ATCC; TIB-68
DR   BCRC; 60176
DR   BioSample; SAMN11397664
DR   CCRID; 1101MOU-PUMC000029
DR   CLS; 400381
DR   JCRB; JCRB9093
DR   KCB; KCB 2012094YJ
DR   RCB; RCB0035
DR   Wikidata; Q54993760
RX   PubMed=3005406;
RX   PubMed=3792703;
RX   PubMed=4543620;
RX   PubMed=5259325;
RX   PubMed=6170720;
RX   PubMed=6687612;
RX   PubMed=25277546;
RX   PubMed=31220119;
WW   https://web.archive.org/web/20201109215324/www.infarktforschung.de/macrophages_cell_lines.html
CC   Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
CC   Doubling time: 18 hours (Note=In 2% FCS) (PubMed=3005406).
CC   Transformant: DrugBank; DB11057; Mineral oil.
CC   Omics: SNP array analysis.
CC   Misspelling: WEIHI3; Note=Occasionally.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Breed/subspecies: BALB/c.
ST   Source(s): PubMed=31220119
ST   Mouse STR 1-1: 15,16,18
ST   Mouse STR 1-2: 17
ST   Mouse STR 11-2: 18,19
ST   Mouse STR 12-1: 16,17
ST   Mouse STR 13-1: 15.2,16.2
ST   Mouse STR 15-3: 22.3,23.3,25.5
ST   Mouse STR 17-2: 16
ST   Mouse STR 18-3: 18
ST   Mouse STR 19-2: 12,13
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14,15
ST   Mouse STR 4-2: 21.3
ST   Mouse STR 5-5: 14
ST   Mouse STR 6-4: 18,19,20,21
ST   Mouse STR 6-7: 12,13,14
ST   Mouse STR 7-1: 25.2,26.2,27.2
ST   Mouse STR 8-1: 13,14
ST   Mouse STR X-1: 26,27
DI   NCIt; C21604; Mouse leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 25
//
RX   PubMed=3005406; DOI=10.4049/jimmunol.136.6.2181;
RA   Morel P.A., Manolagas S.C., Provvedini D.M., Wegmann D.R.,
RA   Chiller J.M.;
RT   "Interferon-gamma-induced IA expression in WEHI-3 cells is enhanced by
RT   the presence of 1,25-dihydroxyvitamin D3.";
RL   J. Immunol. 136:2181-2186(1986).
//
RX   PubMed=3792703; DOI=10.1111/j.1432-0436.1986.tb00568.x;
RA   Leenen P.J.M., Jansen A.M.A.C., van Ewijk W.;
RT   "Murine macrophage cell lines can be ordered in a linear
RT   differentiation sequence.";
RL   Differentiation 32:157-164(1986).
//
RX   PubMed=4543620; DOI=10.3181/00379727-144-37688;
RA   Rollinghoff M., Warner N.L.;
RT   "Specificity of in vivo tumor rejection assessed by mixing immune
RT   spleen cells with target and unrelated tumor cells.";
RL   Proc. Soc. Exp. Biol. Med. 144:813-818(1973).
//
RX   PubMed=5259325; DOI=10.1093/jnci/43.4.963;
RA   Warner N.L., Moore M.A.S., Metcalf D.;
RT   "A transplantable myelomonocytic leukemia in BALB-c mice: cytology,
RT   karyotype, and muramidase content.";
RL   J. Natl. Cancer Inst. 43:963-982(1969).
//
RX   PubMed=6170720; DOI=10.1084/jem.154.5.1419;
RA   McKean D.J., Infante A.J., Nilson A., Kimoto M., Fathman C.G.,
RA   Walker E., Warner N.L.;
RT   "Major histocompatibility complex-restricted antigen presentation to
RT   antigen-reactive T cells by B lymphocyte tumor cells.";
RL   J. Exp. Med. 154:1419-1431(1981).
//
RX   PubMed=6687612;
RA   de Weger R.A., van Loveren H., van Basten C.D.H., Oskam R.,
RA   van der Zeijst B.A.M., Den Otter W.;
RT   "Functional activities of the NCTC 1469 macrophage-like cell line:
RT   comparison of the NCTC 1469 cell line with various other
RT   macrophage-like cell lines.";
RL   J. Reticuloendothel. Soc. 33:55-66(1983).
//
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847;
RA   Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W.,
RA   Morse H.C. III, Pardo-Manuel de Villena F.;
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).
//
RX   PubMed=31220119; DOI=10.1371/journal.pone.0218412;
RA   Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S.,
RA   Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H.,
RA   Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B.,
RA   Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.;
RT   "Interlaboratory study to validate a STR profiling method for
RT   intraspecies identification of mouse cell lines.";
RL   PLoS ONE 14:E0218412-E0218412(2019).
//