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Cellosaurus MCF-10F (CVCL_3633)

[Text version]

Cell line name MCF-10F
Synonyms MCF 10F; MCF10F; MCF-10 Floating; Michigan Cancer Foundation-10F
Accession CVCL_3633
Resource Identification Initiative To cite this cell line use: MCF-10F (RRID:CVCL_3633)
Comments Part of: ICBP43 breast cancer cell line panel.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*01:01,33:01
HLA-BB*40:01,55:01
HLA-CC*07:02,03:03
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0598 (MCF-10A)
Originate from same individual CVCL_5553 ! MCF-10-2F
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,12
D5S81810,13
D7S82010,11
D13S3178,9
D16S53911,12
TH018,9.3
TPOX9,11
vWA15,17

Run an STR similarity search on this cell line
Web pages http://lincs.hms.harvard.edu/resources/reagents/icbp43/
Publications

PubMed=1975513
Soule H.D., Maloney T.M., Wolman S.R., Peterson W.D. Jr., Brenz R., McGrath C.M., Russo J., Pauley R.J., Jones R.F., Brooks S.C.
Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10.
Cancer Res. 50:6075-6086(1990)

Patent=US5436152
Soule H.D., McGrath C.M.
Immortal human mammary epithelial cell lines.
Patent number US5436152, 25-Jul-1995

PubMed=12353263; DOI=10.1002/gcc.10107
Popovici C., Basset C., Bertucci F., Orsetti B., Adelaide J., Mozziconacci M.-J., Conte N., Murati A., Ginestier C., Charafe-Jauffret E., Ethier S.P., Lafage-Pochitaloff M., Theillet C., Birnbaum D., Chaffanet M.
Reciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene.
Genes Chromosomes Cancer 35:204-218(2002)

PubMed=12800145; DOI=10.1002/gcc.10218
Adelaide J., Huang H.-E., Murati A., Alsop A.E., Orsetti B., Mozziconacci M.-J., Popovici C., Ginestier C., Letessier A., Basset C., Courtay-Cahen C., Jacquemier J., Theillet C., Birnbaum D., Edwards P.A.W., Chaffanet M.
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Genes Chromosomes Cancer 37:333-345(2003)

PubMed=18056439; DOI=10.1158/0008-5472.CAN-07-1371
Huang Y., Fernandez S.V., Goodwin S., Russo P.A., Russo I.H., Sutter T.R., Russo J.
Epithelial to mesenchymal transition in human breast epithelial cells transformed by 17beta-estradiol.
Cancer Res. 67:11147-11157(2007)

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y., Mills G.B., Cho R.J., Collisson E.A., van't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

Cross-references
Cell line collections ATCC; CRL-10318
Cell line databases/resources LINCS_HMS; 50584
LINCS_LDP; LCL-2102
Ontologies BTO; BTO:0003900
CLO; CLO_0007600
Gene expression databases GEO; GSM115080
GEO; GSM115081
GEO; GSM115082
GEO; GSM1172974
GEO; GSM1172883
Other Wikidata; Q54904300
Polymorphism and mutation databases Cosmic; 1136377
Entry history
Entry creation04-Apr-2012
Last entry updated13-Nov-2018
Version number22