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Cellosaurus Hep-G2/2.2.1 (CVCL_3701)

[Text version]

Cell line name Hep-G2/2.2.1
Synonyms HEP-G2/2.2.1; HEP G2/2.2.1; HepG2/2.2.1; Hep 2.2.1
Accession CVCL_3701
Resource Identification Initiative To cite this cell line use: Hep-G2/2.2.1 (RRID:CVCL_3701)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11997.
Population: Caucasian.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S82010
D13S3179,13
D16S53912,13
TH019
TPOX8,9
vWA17

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Publications

Patent=US5821057
Chiang J.Y.L., Stroup D.
Assay for agents that affect cholesterol 7alpha-hydroxylase expression and a characterization of its regulatory elements.
Patent number US5821057, 13-Oct-1998

Cross-references
Cell line collections ATCC; CRL-11997
BCRC; 60364
Ontologies BTO; BTO:0004572
CLO; CLO_0003705
Other Wikidata; Q54882786
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number21