Cellosaurus JSC-1 (CVCL_3728)

Cell line name JSC-1
Synonyms JSC1
Accession CVCL_3728
Secondary accession CVCL_B054
Resource Identification Initiative To cite this cell line use: JSC-1 (RRID:CVCL_3728)
Comments Doubling time: 48 hours (PubMed=11024147).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Misspelling: JCS-1; Occasionally.
Derived from sampling site: Ascites.
Disease Primary effusion lymphoma (NCIt: C6915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,11
D13S3179,14
D16S53911,12
D5S81812
D7S8209
TH016,9
TPOX8,11
vWA14,18
Publications

PubMed=11024147; DOI=10.1128/JVI.74.21.10187-10193.2000
Cannon J.S., Ciufo D., Hawkins A.L., Griffin C.A., Borowitz M.J., Hayward G.S., Ambinder R.F.
A new primary effusion lymphoma-derived cell line yields a highly infectious Kaposi's sarcoma herpesvirus-containing supernatant.
J. Virol. 74:10187-10193(2000)

PubMed=15613351; DOI=10.1128/JVI.79.2.1244-1251.2005
Fan W., Bubman D., Chadburn A., Harrington W.J. Jr., Cesarman E., Knowles D.M.
Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association.
J. Virol. 79:1244-1251(2005)

PubMed=21685375; DOI=10.1182/blood-2010-12-323659
Roy D., Sin S.-H., Damania B., Dittmer D.P.
Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.
Blood 118:E32-E39(2011)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-2769 - Discontinued
ATCC; JHU-32 - Discontinued
Cell line databases/resources Cosmic-CLP; 1327769
GDSC; 1327769
LINCS_LDP; LCL-1959
Ontologies CLO; CLO_0007039
Biological sample resources BioSample; SAMN03471783
Gene expression databases GEO; GSM634739
GEO; GSM710424
GEO; GSM710440
GEO; GSM827379
GEO; GSM1669964
Polymorphism and mutation databases Cosmic; 1588564