ID   JSC-1
AC   CVCL_3728
AS   CVCL_B054
SY   JSC1
DR   CLO; CLO_0007039
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-2769
DR   ATCC; JHU-32
DR   BioSample; SAMN03471783
DR   CCLE; JSC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
DR   Cell_Model_Passport; SIDM00688
DR   Cosmic; 1588564
DR   Cosmic-CLP; 1327769
DR   DepMap; ACH-002253
DR   GDSC; 1327769
DR   GEO; GSM634739
DR   GEO; GSM710424
DR   GEO; GSM710440
DR   GEO; GSM827379
DR   GEO; GSM1669964
DR   LINCS_LDP; LCL-1959
DR   PharmacoDB; JSC1_711_2019
DR   Wikidata; Q54899065
RX   PubMed=11024147;
RX   PubMed=15613351;
RX   PubMed=20215515;
RX   PubMed=21685375;
RX   PubMed=27397505;
RX   PubMed=30894373;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: COSMIC cell lines project.
CC   Doubling time: 48 hours (PubMed=11024147).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
CC   Omics: Deep exome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0.79%; Native American=0.09%; East Asian, North=0.94%; East Asian, South=0%; South Asian=1.9%; European, North=65.05%; European, South=31.24% (PubMed=30894373).
CC   Misspelling: JCS-1; Occasionally.
CC   Discontinued: ATCC; CRL-2769; true.
CC   Discontinued: ATCC; JHU-32; true.
CC   Derived from sampling site: Ascites.
ST   Source(s): ATCC; Cosmic-CLP
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 9,14
ST   D16S539: 11,12
ST   D5S818: 12
ST   D7S820: 9
ST   TH01: 6,9
ST   TPOX: 8,11
ST   vWA: 14,18
DI   NCIt; C6915; Primary effusion lymphoma
DI   ORDO; Orphanet_48686; Primary effusion lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   52Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 12-03-20; Version: 25
//
RX   PubMed=11024147; DOI=10.1128/JVI.74.21.10187-10193.2000;
RA   Cannon J.S., Ciufo D., Hawkins A.L., Griffin C.A., Borowitz M.J.,
RA   Hayward G.S., Ambinder R.F.;
RT   "A new primary effusion lymphoma-derived cell line yields a highly
RT   infectious Kaposi's sarcoma herpesvirus-containing supernatant.";
RL   J. Virol. 74:10187-10193(2000).
//
RX   PubMed=15613351; DOI=10.1128/JVI.79.2.1244-1251.2005;
RA   Fan W., Bubman D., Chadburn A., Harrington W.J. Jr., Cesarman E.,
RA   Knowles D.M.;
RT   "Distinct subsets of primary effusion lymphoma can be identified based
RT   on their cellular gene expression profile and viral association.";
RL   J. Virol. 79:1244-1251(2005).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=21685375; DOI=10.1182/blood-2010-12-323659;
RA   Roy D., Sin S.-H., Damania B., Dittmer D.P.;
RT   "Tumor suppressor genes FHIT and WWOX are deleted in primary effusion
RT   lymphoma (PEL) cell lines.";
RL   Blood 118:E32-E39(2011).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M.,
RA   Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M.,
RA   Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A.,
RA   Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//