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Cellosaurus MeT-5A (CVCL_3749)

[Text version]

Cell line name MeT-5A
Synonyms MeT 5A; MeT5A; Met5A; MET5A; Mesothelial cells transfected with pRSV-T 5A
Accession CVCL_3749
Resource Identification Initiative To cite this cell line use: MeT-5A (RRID:CVCL_3749)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [pRSV-T].
Omics: Transcriptome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_LJ67 (MeT-5A/EJ-ras)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
STR profile Source(s): ATCC


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Reddel R.R., Yang K., Rhim J.S., Brash D.E., Su R.T., Lechner J.F., Gerwin B.I., Harris C.C., Amstad P.
Immortalized human bronchial epithelial mesothelial cell lines.
Patent number US4885238, 05-Dec-1989

Ke Y., Reddel R.R., Gerwin B.I., Reddel H.K., Somers A.N., McMenamin M.G., LaVeck M.A., Stahel R.A., Lechner J.F., Harris C.C.
Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma.
Am. J. Pathol. 134:979-991(1989)

PubMed=9533946; DOI=10.1165/ajrcmb.18.4.2943
Kahlos K., Anttila S., Asikainen T., Kinnula K., Raivio K.O., Mattson K., Linnainmaa K., Kinnula V.L.
Manganese superoxide dismutase in healthy human pleural mesothelium and in malignant pleural mesothelioma.
Am. J. Respir. Cell Mol. Biol. 18:570-580(1998)

PubMed=15920167; DOI=10.1016/S0002-9440(10)62492-3
Gordon G.J., Rockwell G.N., Jensen R.V., Rheinwald J.G., Glickman J.N., Aronson J.P., Pottorf B.J., Nitz M.D., Richards W.G., Sugarbaker D.J., Bueno R.
Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.
Am. J. Pathol. 166:1827-1840(2005)

PubMed=17331233; DOI=10.1186/1471-2164-8-62
Nymark P., Lindholm P.M., Korpela M.V., Lahti L., Ruosaari S., Kaski S., Hollmen J., Anttila S., Kinnula V.L., Knuutila S.
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines.
BMC Genomics 8:62-62(2007)

PubMed=22576795; DOI=10.3892/or.2012.1763
Ashinuma H., Takiguchi Y., Kitazono S., Kitazono-Saitoh M., Kitamura A., Chiba T., Tada Y., Kurosu K., Sakaida E., Sekine I., Tanabe N., Iwama A., Yokosuka O., Tatsumi K.
Antiproliferative action of metformin in human lung cancer cell lines.
Oncol. Rep. 28:8-14(2012)

PubMed=24926545; DOI=10.1097/JTO.0000000000000202
Riquelme E., Suraokar M.B., Rodriguez J., Mino B., Lin H.Y., Rice D.C., Tsao A., Wistuba I.I.
Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma.
J. Thorac. Oncol. 9:998-1007(2014)

PubMed=26011428; DOI=10.1111/cas.12698
Hakiri S., Osada H., Ishiguro F., Murakami H., Murakami-Tonami Y., Yokoi K., Sekido Y.
Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells.
Cancer Sci. 106:990-999(2015)

PubMed=28553954; DOI=10.1038/onc.2017.147
Kato T., Sato T., Yokoi K., Sekido Y.
E-cadherin expression is correlated with focal adhesion kinase inhibitor resistance in merlin-negative malignant mesothelioma cells.
Oncogene 36:5522-5531(2017)

Cell line collections ATCC; CRL-9444
BCRC; 60352
Ontologies CLO; CLO_0007680
EFO; EFO_0001218
Biological sample resources BioSample; SAMN03471216
Gene expression databases GEO; GSM49613
GEO; GSM139667
GEO; GSM139668
GEO; GSM139669
GEO; GSM139760
GEO; GSM139761
Other Wikidata; Q54905322
Entry history
Entry creation04-Apr-2012
Last entry updated07-Sep-2018
Version number14