Cell line name | OVK18 | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | OVK-18; OVK#18 | ||||||||||||||||||||
Accession | CVCL_3770 | ||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: OVK18 (RRID:CVCL_3770) | ||||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Population: Japanese. Doubling time: ~48 hours (PubMed=6584390). Microsatellite instability: Instable (MSI-high) (PubMed=31068700; Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: Genome sequenced. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||||
Sequence variations | Heterozygous for JAK2 p.Leu437fs*1 (c.1305delT) (CCLE; Cosmic-CLP).Heterozygous for KRAS p.Ala59Gly (c.176C>G) (CCLE; Cosmic-CLP).Heterozygous for SMAD2 p.Tyr366fs*17 (c.1096delT) (CCLE; Cosmic-CLP).Heterozygous for SMARCA4 p.Pro109fs*194 (c.322delC) (CCLE; Cosmic-CLP).Heterozygous for TP53 p.Pro152Argfs*18 (c.455delC) (ClinVar=VCV000634779) (CCLE; Cosmic-CLP). | ||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||||
Disease | Ovarian endometrioid adenocarcinoma (NCIt: C7979) Endometrioid carcinoma of ovary (ORDO: Orphanet_454723) Derived from metastatic site: Ascites. | ||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
| ||||||||||||||||||||
Hierarchy | Children:
| ||||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||||
Age at sampling | 49Y | ||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; PubMed=30485824; RCB; TKG Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||
Publications | PubMed=6584390; DOI=10.1016/0090-8258(84)90217-8 PubMed=22460905; DOI=10.1038/nature11003 PubMed=22705003; DOI=10.1016/j.humpath.2012.03.011 PubMed=23839242; DOI=10.1038/ncomms3126 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=32612269; DOI=10.1038/s41598-020-67533-1 | ||||||||||||||||||||
Cross-references | |||||||||||||||||||||
Cell line collections | RCB; RCB1903
TKG; TKG 0323 | ||||||||||||||||||||
Cell line databases/resources | CCLE; OVK18_OVARY
Cell_Model_Passport; SIDM00238 Cosmic-CLP; 1480371 DepMap; ACH-000947 | ||||||||||||||||||||
Ontologies | CLO; CLO_0051452 | ||||||||||||||||||||
Biological sample resources | BioSample; SAMN03472087
BioSample; SAMN10987740 | ||||||||||||||||||||
Chemistry resources | GDSC; 1480371
PharmacoDB; OVK18_1223_2019 | ||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610 GEO; GSM887486 GEO; GSM888568 GEO; GSM1670322 | ||||||||||||||||||||
Other | Wikidata; Q54937028 | ||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 1066216
Cosmic; 1708385 IARC_TP53; 28375 LiGeA; CCLE_457 Progenetix; CVCL_3770 | ||||||||||||||||||||
Entry history | |||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||||
Version number | 22 |