Cellosaurus OVK18 (CVCL_3770)

Cell line name OVK18
Synonyms OVK-18; OVK#18
Accession CVCL_3770
Resource Identification Initiative To cite this cell line use: OVK18 (RRID:CVCL_3770)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Microsatellite instability: Instable (MSI-high) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_7171 (OVK18#102)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB; TKG

Markers:
AmelogeninX
CSF1PO10,11
D13S3178,12
D16S5399,11
D5S8188,13
D7S8208 (RCB)
8,13,14 (Cosmic-CLP; TKG)
TH017
TPOX8,11
vWA17,18
Publications

PubMed=6584390; DOI=10.1016/0090-8258(84)90217-8
Uehara S., Abe H., Hoshiai H., Yajima A., Suzuki M.
Establishment and characterization of ovarian endometrioid carcinoma cell line.
Gynecol. Oncol. 17:314-325(1984)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23839242; DOI=10.1038/ncomms3126
Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.
Evaluating cell lines as tumour models by comparison of genomic profiles.
Nat. Commun. 4:2126-2126(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections RCB; RCB1903
TKG; TKG 0323
Cell line databases/resources CCLE; OVK18_OVARY
Cosmic-CLP; 1480371
GDSC; 1480371
Ontologies CLO; CLO_0051452
Biological sample resources BioSample; SAMN03472087
Gene expression databases GEO; GSM887486
GEO; GSM888568
GEO; GSM1670322
Polymorphism and mutation databases Cosmic; 1066216
Cosmic; 1708385