Home  |  Contact

Cellosaurus RKO-AS45-1 (CVCL_3786)

[Text version]

Cell line name RKO-AS45-1
Synonyms RKO-AS-45-1; RKOAS451; RKO_AS45
Accession CVCL_3786
Resource Identification Initiative To cite this cell line use: RKO-AS45-1 (RRID:CVCL_3786)
Comments Transfected with: HGNC; 4095; GADD45A.
Omics: Transcriptome analysis.
Misspelling: RKO-AS4; In Cosmic 1187316.
Sequence variations Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (from parent cell line).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0504 (RKO)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO8,11
D5S81811,13
D7S8208,10
D13S3178,11
D16S53912.1,13
TH016,10
TPOX10,11
vWA16,24

Run an STR similarity search on this cell line
Publications

PubMed=7973727; DOI=10.1126/science.7973727
Smith M.L., Chen I.T., Zhan Q., Bae I., Chen C.-Y., Gilmer T.M., Kastan M.B., O'Connor P.M., Fornace A.J. Jr.
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.
Science 266:1376-1380(1994)

Cross-references
Cell line collections ATCC; CRL-2579
Cell line databases/resources CCRID; 3101HUMTCHu117
Ontologies BTO; BTO:0001892
CLO; CLO_0008826
Biological sample resources BioSample; SAMN03471685
Gene expression databases GEO; GSM206539
GEO; GSM274767
GEO; GSM274768
Other Wikidata; Q54950557
Polymorphism and mutation databases Cosmic; 1187316
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number22