ID   RWPE-2
AC   CVCL_3792
SY   RWPE2
DR   BTO; BTO:0005994
DR   CLO; CLO_0008906
DR   EFO; EFO_0007610
DR   ATCC; CRL-11610
DR   cancercelllines; CVCL_3792
DR   CCRID; 4201HUM-CCTCC00179
DR   CCTCC; GDC0179
DR   Cell_Model_Passport; SIDM01234
DR   ENCODE; ENCBS796LYI
DR   ENCODE; ENCBS942OEI
DR   GEO; GSM827388
DR   KCB; KCB 2013044YJ
DR   Lonza; 1673
DR   Progenetix; CVCL_3792
DR   Wikidata; Q54951498
RX   Patent=US6255058;
RX   PubMed=9018337;
RX   PubMed=9214605;
RX   PubMed=9214606;
RX   PubMed=12725112;
RX   PubMed=20215515;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11610.
CC   Population: Caucasian.
CC   Transfected with: UniProtKB; P01117; Kirsten murine sarcoma virus Ki-Ras.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
ST   Source(s): ATCC
ST   Amelogenin: X,Y
ST   CSF1PO: 13
ST   D13S317: 8,14
ST   D16S539: 9,11
ST   D5S818: 12,15
ST   D7S820: 10,11
ST   TH01: 8,9.3
ST   TPOX: 8,11
ST   vWA: 14,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3791 ! RWPE-1
SX   Male
AG   54Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 28
//
RX   Patent=US6255058;
RA   Webber M.M., Rhim J.S.;
RT   "Immortalized and malignant human prostatic cell lines.";
RL   Patent number US6255058, 03-Jul-2001.
//
RX   PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H;
RA   Webber M.M., Bello D., Quader S.T.A.;
RT   "Immortalized and tumorigenic adult human prostatic epithelial cell
RT   lines: characteristics and applications Part 2. Tumorigenic cell
RT   lines.";
RL   Prostate 30:58-64(1997).
//
RX   PubMed=9214605; DOI=10.1093/carcin/18.6.1215;
RA   Bello D., Webber M.M., Kleinman H.K., Wartinger D.D., Rhim J.S.;
RT   "Androgen responsive adult human prostatic epithelial cell lines
RT   immortalized by human papillomavirus 18.";
RL   Carcinogenesis 18:1215-1223(1997).
//
RX   PubMed=9214606; DOI=10.1093/carcin/18.6.1225;
RA   Webber M.M., Bello D., Kleinman H.K., Hoffman M.P.;
RT   "Acinar differentiation by non-malignant immortalized human prostatic
RT   epithelial cells and its loss by malignant cells.";
RL   Carcinogenesis 18:1225-1231(1997).
//
RX   PubMed=12725112; DOI=10.1385/1-59259-372-0:21;
RA   Russell P.J., Kingsley E.A.;
RT   "Human prostate cancer cell lines.";
RL   Methods Mol. Med. 81:21-39(2003).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//