Cellosaurus SW527 (CVCL_3799)

Cell line name SW527
Synonyms SW-527; SW 527
Accession CVCL_3799
Resource Identification Initiative To cite this cell line use: SW527 (RRID:CVCL_3799)
Comments Problematic cell line: Contaminated. Shown to be a SW480 derivative (PubMed=288927, PubMed=20143388).
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
From: Scott and White Clinic; Temple; Texas; USA.
Sequence variation: APC p.Gln1338Ter (from parent cell line).
Sequence variation: KRAS p.Gly12Val (from parent cell line).
Sequence variation: TP53 p.Arg273His and p.Pro309Ser (from parent cell line).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=25877200

Markers:
AmelogeninX
CSF1PO13,14
D13S31712
D16S5399,13
D18S5113
D21S1130,30.2
D3S135815,16
D5S81813
D7S8208
D8S117913
FGA24
Penta D9,15
Penta E10
TH018
TPOX11
vWA16
Web pages http://colt.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=SW527
http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=288927; DOI=10.1093/jnci/63.3.635
Lelbovitz A., Wright W.C., Pathak S., Siciliano M.J., Daniels W.P., Fogh H., Fogh J.
Detection and analysis of a glucose 6-phosphate dehydrogenase phenotype B cell line contamination.
J. Natl. Cancer Inst. 63:635-645(1979)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections ATCC; CRL-7940
Cell line databases/resources LINCS_HMS; 50046
LINCS_LDP; LCL-1474
Ontologies CLO; CLO_0009219
EFO; EFO_0005462
Biological sample resources BioSample; SAMN03151930
BioSample; SAMN03481115
Polymorphism and mutation databases Cosmic; 1047713