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Cellosaurus MAT-LyLu (CVCL_3848)

[Text version]
Cell line name MAT-LyLu
Synonyms Mat-Ly-Lu; MATLyLu; R3327-MATLyLu; R3327-MatLyLu; Dunning R 3327 MAT LyLu; Metastatic AT tumor able to disseminate to lymph nodes and lung
Accession CVCL_3848
Secondary accession CVCL_2168
Resource Identification Initiative To cite this cell line use: MAT-LyLu (RRID:CVCL_3848)
Comments Doubling time: ~15 hours (DSMZ=ACC-609).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Adenocarcinoma of the rat prostate (NCIt: C64013)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Copenhagen.
Hierarchy Parent: CVCL_3568 (R-3327-AT-1)
Children:
CVCL_Y659 (MAT-LyLu-B-1)CVCL_3849 (MAT-LyLu-B-2)
Sex of cell Male
Age at sampling 1Y10M
Category Cancer cell line
Publications

PubMed=7251319
Isaacs J.T., Yu G.W., Coffey D.S.
The characterization of a newly identified, highly metastatic variety of Dunning R 3327 rat prostatic adenocarcinoma system: the MAT LyLu tumor.
Invest. Urol. 19:20-23(1981)

PubMed=3774632; DOI=10.1002/pros.2990090306
Isaacs J.T., Isaacs W.B., Feitz W.F.J., Scheres J.
Establishment and characterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers.
Prostate 9:261-281(1986)

PubMed=3174494; DOI=10.1002/pros.2990130208
Isaacs J.T., Hukku B.
Nonrandom involvement of chromosome 4 in the progression of rat prostatic cancer.
Prostate 13:165-188(1988)

PubMed=7910810; DOI=10.1002/ijc.2910570519
Bashir I., Sikora K., Abel P., Foster C.S.
Establishment and in vivo characterization of multidrug-resistant Dunning R3327 rat prostate-carcinoma cell-lines.
Int. J. Cancer 57:719-726(1994)

PubMed=8687134
Pandalai P.K., Pilat M.J., Yamazaki K., Naik H., Pienta K.J.
The effects of omega-3 and omega-6 fatty acids on in vitro prostate cancer growth.
Anticancer Res. 16:815-820(1996)

PubMed=23467722; DOI=10.3892/or.2013.2323
Musialik E., Ryszawy D., Madeja Z., Korohoda W.
Morpho-physiological heterogeneity of cells within two rat prostate carcinoma cell lines AT-2 and MAT-LyLu differing in the degree of malignancy observed by cell cloning and the effects of caffeine, theophylline and papaverine upon a proportion of the clones.
Oncol. Rep. 29:1789-1796(2013)

Cross-references
Cell line collections (Providers) ATCC; JHU-5 - Discontinued
ATCC; JHU-92 - Discontinued
DSMZ; ACC-609
ECACC; 94101454
Cell line databases/resources CLO; CLO_0007541
CLDB; cl3338
DSMZCellDive; ACC-609
Anatomy/cell type resources BTO; BTO:0003306
Chemistry resources ChEMBL-Cells; CHEMBL3307987
ChEMBL-Targets; CHEMBL612579
PubChem_Cell_line; CVCL_3848
Encyclopedic resources Wikidata; Q54904059
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18