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Cellosaurus LN-340 (CVCL_3955)

Cell line name LN-340
Synonyms LN 340; LN340
Accession CVCL_3955
Resource Identification Initiative To cite this cell line use: LN-340 (RRID:CVCL_3955)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 30 hours (PubMed=25984343).
Omics: shRNA library screening.
Sequence variations TP53 p.Arg181Pro (c.542G>C) (PubMed=10416987).
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): PubMed=22570425

Markers:
AmelogeninX,Y
CSF1PO11
D3S135815
D5S81811,12
D7S82011,12
D8S117914
D13S31711,12
D16S53911,14
D18S5114,18
D21S1128,32.2
FGA21,25
Penta D12,15
Penta E5,9
TH017,9.3
TPOX8
vWA17
Publications

PubMed=7693337
Li H., Hamou M.-F., de Tribolet N., Jaufeerally R., Hofmann M., Diserens A.-C., Van Meir E.G.
Variant CD44 adhesion molecules are expressed in human brain metastases but not in glioblastomas.
Cancer Res. 53:5345-5349(1993)

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x
Ishii N., Maier D., Merlo A., Tada M., Sawamura Y., Diserens A.-C., Van Meir E.G.
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=22570425; DOI=10.1093/neuonc/nos072
Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K., Hamou M.-F., Delorenzi M., Hegi M.E.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

Cross-references
Cell line databases/resources CCLE; LN340_CENTRAL_NERVOUS_SYSTEM
Ontologies BTO; BTO:0004458
Other Wikidata; Q54902777
Polymorphism and mutation databases Cosmic; 849865
Cosmic; 2367494
Cosmic; 2516028