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Cellosaurus LN-464 (CVCL_3962)

[Text version]

Cell line name LN-464
Synonyms LN 464; LN464
Accession CVCL_3962
Resource Identification Initiative To cite this cell line use: LN-464 (RRID:CVCL_3962)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 35 hours (PubMed=25984343).
Omics: shRNA library screening.
Sequence variations TP53 p.Phe113Ser (c.338T>C) (PubMed=10416987).
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): PubMed=22570425

Markers:
AmelogeninX
CSF1PO11
D3S135816
D5S81812
D7S82010,13
D8S117912,13
D13S31711,13
D16S53911
D18S5116
D21S1128
FGA22
Penta D9
Penta E10,14
TH019
TPOX9,12
vWA14,17,18

Run an STR similarity search on this cell line
Publications

PubMed=7693337
Li H., Hamou M.-F., de Tribolet N., Jaufeerally R., Hofmann M., Diserens A.-C., Van Meir E.G.
Variant CD44 adhesion molecules are expressed in human brain metastases but not in glioblastomas.
Cancer Res. 53:5345-5349(1993)

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x
Ishii N., Maier D., Merlo A., Tada M., Sawamura Y., Diserens A.-C., Van Meir E.G.
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=22570425; DOI=10.1093/neuonc/nos072
Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K., Hamou M.-F., Delorenzi M., Hegi M.E.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

Cross-references
Cell line databases/resources CCLE; LN464_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00058
Ontologies BTO; BTO:0004451
Other Wikidata; Q54902786
Polymorphism and mutation databases Cosmic; 849873
Cosmic; 2367498
Cosmic; 2516032