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Cellosaurus NCI-H1334 (CVCL_3971)

[Text version]

Cell line name NCI-H1334
Synonyms H1334; H-1334
Accession CVCL_3971
Resource Identification Initiative To cite this cell line use: NCI-H1334 (RRID:CVCL_3971)
Comments Problematic cell line: Probably contaminated. The STR profile is identical to that of the NCI-H322 cell line. Originally thought to originate from a 56 year old male patient with a large cell lung carcinoma.
Sequence variations Homozygous for TP53 p.Arg248Leu (c.743G>T) (ClinVar=VCV000230253) (from parent cell line).
TP53 p.Glu224Asp (c.672G>C) (PubMed=1311061).
Disease Minimally invasive lung adenocarcinoma (NCIt: C2923)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1556 (NCI-H322)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=11416159

Markers:
AmelogeninX
CSF1PO12
D5S81811
D7S82011
D8S117912,15
D13S31712
D16S53911,12
D18S5117
D21S1128
FGA22
TH017
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=2386953
Gazdar A.F., Linnoila R.I., Kurita Y., Oie H.K., Mulshine J.L., Clark J.C., Whitsett J.A.
Peripheral airway cell differentiation in human lung cancer cell lines.
Cancer Res. 50:5481-5487(1990)

PubMed=1311061
Mitsudomi T., Steinberg S.M., Nau M.M., Carbone D., D'Amico D., Bodner S., Oie H.K., Linnoila R.I., Mulshine J.L., Minna J.D., Gazdar A.F.
p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.
Oncogene 7:171-180(1992)

PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. 63 Suppl. 24:32-91(1996)

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Modi S., Kubo A., Oie H., Coxon A.B., Rehmatulla A., Kaye F.J.
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=31803961; DOI=10.1002/jcb.29564
Mulshine J.L., Ujhazy P., Antman M., Burgess C.M., Kuzmin I., Bunn P.A. Jr., Johnson B.E., Roth J.A., Pass H.I., Ross S.M., Aldige C.R., Wistuba I.I., Minna J.D.
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

Cross-references
Cell line collections ATCC; CRL-5863 - Discontinued
KCLB; 91334
Ontologies BTO; BTO:0003011
EFO; EFO_0003117
Other Wikidata; Q54907791
Polymorphism and mutation databases Cosmic; 844596
Cosmic; 877419
Cosmic; 903586
Cosmic; 980972
Cosmic; 1032444
Cosmic; 1152509
Cosmic; 1891888
IARC_TP53; 488
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number14