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Cellosaurus A-9 (CVCL_3984)

[Text version]
Cell line name A-9
Synonyms A9; A9 (Hamprecht); A9(Hamprecht); AG 9; GM00346; GM-346; GM346; GM00346B
Accession CVCL_3984
Resource Identification Initiative To cite this cell line use: A-9 (RRID:CVCL_3984)
Comments Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Doubling time: ~1 day (Note=Lot 07122006) (JCRB=JCRB0211).
Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine.
Miscellaneous: ECACC has two catalogue entries for A-9 which differ in that they were deposited by different groups: A9 (ECACC=85011426) and A9 (Hamprecht) (ECACC=08062526).
Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/An.
Hierarchy Parent: CVCL_0462 (NCTC clone 929)
Children:
CVCL_4091 (54SCC2)CVCL_4092 (54SCC3)CVCL_4093 (54SCC7)
CVCL_9095 (A9 L hD2 S.C. 18)CVCL_A2ZV (A9-PM)CVCL_2830 (A9(An4)-2)
CVCL_2831 (A9(Bsr10))CVCL_2832 (A9(BsrX))CVCL_1P03 (A9(GM0194)-3)
CVCL_2825 (A9(GM0439)-1)CVCL_1P04 (A9(GM1533)-1)CVCL_1P05 (A9(GM1695)-3)
CVCL_1P06 (A9(GM1695)-4)CVCL_1P07 (A9(GM1695)-5)CVCL_2826 (A9(GM2621)-4)
CVCL_1P08 (A9(GM2859)-3)CVCL_1P09 (A9(GM2859)-4)CVCL_1P10 (A9(GM3322)-1)
CVCL_1P11 (A9(GM3322)-2)CVCL_2827 (A9(GM3552)-2)CVCL_2828 (A9(GM3884)-1)
CVCL_1P12 (A9(GM3884)-2)CVCL_1P13 (A9(GM4618)-10)CVCL_1P14 (A9(GM4618)-2)
CVCL_2829 (A9(GM7151)-3)CVCL_2833 (A9(Hygro13))CVCL_2834 (A9(Hygro14))
CVCL_2835 (A9(Hygro21))CVCL_2836 (A9(Hygro22))CVCL_2837 (A9(Neo1))
CVCL_2838 (A9(Neo11))CVCL_2839 (A9(Neo12))CVCL_2840 (A9(Neo15))
CVCL_2841 (A9(Neo16))CVCL_2842 (A9(Neo17))CVCL_2843 (A9(Neo18))
CVCL_2844 (A9(Neo19))CVCL_2845 (A9(Neo2))CVCL_2846 (A9(Neo20))
CVCL_2847 (A9(Neo3))CVCL_2848 (A9(Neo4))CVCL_2849 (A9(Neo5))
CVCL_2850 (A9(Neo6))CVCL_2851 (A9(Neo7))CVCL_2852 (A9(Neo8))
CVCL_2853 (A9(NTI8)-2)CVCL_1P15 (A9+12)CVCL_1P16 (A9+15)
CVCL_1P17 (A9+2)CVCL_1P18 (A9+20)CVCL_1P19 (A9+22)
CVCL_1P20 (A9+3)CVCL_1P21 (A9+5)CVCL_LB84 (A9G TG40)
CVCL_4387 (A9HT)CVCL_1Q12 (CY100)CVCL_1Q05 (CY11)
CVCL_VK20 (CY110)CVCL_1Q13 (CY115)CVCL_VK21 (CY116)
CVCL_VK22 (CY117)CVCL_1Q06 (CY12)CVCL_1Q14 (CY120)
CVCL_VK23 (CY121)CVCL_VK24 (CY122)CVCL_VK34 (CY123)
CVCL_1Q15 (CY124)CVCL_VK35 (CY125)CVCL_VK25 (CY127)
CVCL_1Q16 (CY128)CVCL_1Q07 (CY13)CVCL_VK13 (CY130)
CVCL_VK14 (CY135)CVCL_VK26 (CY138)CVCL_1Q08 (CY14)
CVCL_1Q59 (CY140)CVCL_VK27 (CY148)CVCL_1Q09 (CY15 [Human/mouse hybrid])
CVCL_VK36 (CY150)CVCL_VK28 (CY152)CVCL_1Q17 (CY153)
CVCL_VK29 (CY155)CVCL_1Q18 (CY160)CVCL_VK30 (CY163)
CVCL_1Q19 (CY165)CVCL_VK38 (CY168)CVCL_1Q20 (CY170)
CVCL_VK15 (CY175)CVCL_VK37 (CY177)CVCL_1Q10 (CY18)
CVCL_VK16 (CY180)CVCL_VK17 (CY182)CVCL_VK31 (CY183)
CVCL_1Q21 (CY185)CVCL_1Q11 (CY19)CVCL_VK32 (CY190)
CVCL_1Q22 (CY192)CVCL_VK41 (CY194)CVCL_VK18 (CY196)
CVCL_VK19 (CY197)CVCL_VK33 (CY198)CVCL_1P98 (CY2 [Human/mouse hybrid])
CVCL_1P99 (CY3)CVCL_1Q00 (CY4)CVCL_1Q01 (CY5)
CVCL_1Q02 (CY6)CVCL_1Q03 (CY7)CVCL_1Q04 (CY8)
CVCL_A5VP (F9-11)CVCL_A5VQ (F9-12)CVCL_A5VR (F9-13)
CVCL_A5VS (F9-15)CVCL_A5VT (F9-5)CVCL_1R80 (GM08854)
CVCL_1R81 (GM09142)CVCL_1R83 (GM10063)CVCL_1R88 (GM10322)
CVCL_1R89 (GM10323)CVCL_1R90 (GM10324)CVCL_1R92 (GM10482)
CVCL_1S15 (GM11130)CVCL_DE46 (GM11526)CVCL_1S27 (GM11679)
CVCL_1S29 (GM11686)CVCL_1S30 (GM11687)CVCL_1S31 (GM11688)
CVCL_1S32 (GM11689)CVCL_1S44 (GM11936)CVCL_1S68 (GM13339)
CVCL_1S69 (GM13340)CVCL_1S83 (GM14050)CVCL_1S94 (GM15297)
CVCL_V310 (LIS-3/SV40/A9-B4)CVCL_6C50 (MCH262A1.D6)
Sex of cell Male
Age at sampling 100D
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-110
Mouse STR 1-217,18
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-220.3,21.3
Mouse STR 5-514,15
Mouse STR 6-417,18
Mouse STR 6-712
Mouse STR 7-126,27
Mouse STR 8-116
Mouse STR 11-215,16,17
Mouse STR 12-116
Mouse STR 13-117
Mouse STR 15-325.3
Mouse STR 17-215
Mouse STR 18-316
Mouse STR 19-212
Mouse STR X-126,27

Run an STR similarity search on this cell line
Publications

PubMed=14067106; DOI=10.1073/pnas.50.3.568
Littlefield J.W.
The inosinic acid pyrophosphorylase activity of mouse fibroblasts partially resistant to 8-azaguanine.
Proc. Natl. Acad. Sci. U.S.A. 50:568-573(1963)

PubMed=14213660; DOI=10.1038/2031142a0
Littlefield J.W.
Three degrees of guanylic acid -- inosinic acid pyrophosphorylase deficiency in mouse fibroblasts.
Nature 203:1142-1144(1964)

PubMed=174085; DOI=10.1073/pnas.72.12.4971
Stiles C.D., Desmond W. Jr., Sato G.H., Saier M.H. Jr.
Failure of human cells transformed by simian virus 40 to form tumors in athymic nude mice.
Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975)

PubMed=1260760
Stiles C.D., Desmond W. Jr., Chuman L.M., Sato G.H., Saier M.H. Jr.
Growth control of heterologous tissue culture cells in the congenitally athymic nude mouse.
Cancer Res. 36:1353-1360(1976)

DOI=10.5962/bhl.title.4090
Coriell L.L., Greene A.E.
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=8710496; DOI=10.1093/nar/24.12.2271
McGuigan A., Huxley C.
Replication of yeast DNA and novel chromosome formation in mouse cells.
Nucleic Acids Res. 24:2271-2280(1996)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections (Providers) AddexBio; P0011007/4965
ATCC; CCL-1.4
ATCC; CRL-6319
BCRC; 60138
CCTCC; GDC0259
CLS; 305166
Coriell; GM00346
ECACC; 08062526
ECACC; 85011426
IZSLER; BS CL 209
JCRB; JCRB0211
Cell line databases/resources CLO; CLO_0001618
CLO; CLO_0001620
CLO; CLO_0025566
CLDB; cl219
CLDB; cl220
CCRID; 3101MOUGNM12
TOKU-E; 493
Anatomy/cell type resources BTO; BTO:0002887
Biological sample resources BioSample; SAMN11397623
Chemistry resources ChEMBL-Cells; CHEMBL3307632
ChEMBL-Targets; CHEMBL614518
PubChem_Cell_line; CVCL_3984
Encyclopedic resources Wikidata; Q54606068
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number30