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Cellosaurus PaCa-3 (CVCL_4011)

Cell line name PaCa-3
Synonyms MIA PaCa-3; Mia-Paca 3; Paca-3; PaCa3; PACA3; PC-3; PC 3; PC3; Pc3
Accession CVCL_4011
Resource Identification Initiative To cite this cell line use: PaCa-3 (RRID:CVCL_4011)
Comments Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Pancreatic carcinoma (NCIt: C3850)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
Web pages https://www.cellosaurus.org/pawefish/PancCellLineDescriptions/PaCa-3.html
Publications

CLPUB00718
von Bulow M., Scharfe T., Kloppel G., Kern H.F.
Establishment and characterization of continuous tumor-cell lines from human pancreatic carcinoma in vitro.
Digestion 25:17-18(1982)

PubMed=8194712; DOI=10.1016/0016-5085(94)90422-7
Simon B., Weinel R., Hohne M., Watz J., Schmidt J., Kortner G., Arnold R.
Frequent alterations of the tumor suppressor genes p53 and DCC in human pancreatic carcinoma.
Gastroenterology 106:1645-1651(1994)

PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C
Sirivatanauksorn V., Sirivatanauksorn Y., Gorman P.A., Davidson J.M., Sheer D., Moore P.S., Scarpa A., Edwards P.A.W., Lemoine N.R.
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
Int. J. Cancer 91:350-358(2001)

PubMed=11787853; DOI=10.1007/s004280100474
Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr J.-M., Scarpa A.
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12800145; DOI=10.1002/gcc.10218
Adelaide J., Huang H.-E., Murati A., Alsop A.E., Orsetti B., Mozziconacci M.-J., Popovici C., Ginestier C., Letessier A., Basset C., Courtay-Cahen C., Jacquemier J., Theillet C., Birnbaum D., Edwards P.A.W., Chaffanet M.
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Genes Chromosomes Cancer 37:333-345(2003)

Cross-references
Encyclopedic resources Wikidata; Q54905681
Polymorphism and mutation databases Cosmic; 710862
Cosmic; 1108336
Cosmic; 1320460
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14