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Cellosaurus SCC-12 (CVCL_4026)

[Text version]

Cell line name SCC-12
Synonyms SCC 12; SCC12
Accession CVCL_4026
Resource Identification Initiative To cite this cell line use: SCC-12 (RRID:CVCL_4026)
Sequence variations HRAS p.Gly12Leu (PubMed=11992403).
TP53 p.Val216Gly (c.647T>G) (ClinVar=VCV000376671) (PubMed=11992403).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4027 (SCC-12B)CVCL_4028 (SCC-12F)CVCL_M676 (SCC-12V)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/s/cell-lines-detail-322.html

Rheinwald J.G., Beckett M.A.
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas.
Cancer Res. 41:1657-1663(1981)

PubMed=3360658; DOI=10.1016/0360-3016(88)90013-2
Weichselbaum R.R., Beckett M.A., Dahlberg W., Dritschilo A.
Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones.
Int. J. Radiat. Oncol. Biol. Phys. 14:907-912(1988)

Carey T.E.
Head and neck tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994)

PubMed=11992403; DOI=10.1002/ijc.10321
Popp S., Waltering S., Herbst C., Moll I., Boukamp P.
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas.
Int. J. Cancer 99:352-360(2002)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

Cell line databases/resources IGRhCellID; SCC12%20GSE9585
Other Wikidata; Q54952327
Polymorphism and mutation databases Cosmic; 740989
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number12