ID   SCC-12
AC   CVCL_4026
SY   SCC 12; SCC12
DR   Cosmic; 740989
DR   IGRhCellID; SCC12%20GSE9585
DR   Wikidata; Q54952327
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RX   PubMed=3360658;
RX   PubMed=7214336;
RX   PubMed=11992403;
RX   PubMed=17312569;
CC   Sequence variation: HRAS p.Gly12Leu (PubMed=11992403).
CC   Sequence variation: TP53 p.Val216Gly (c.647T>G) (ClinVar=VCV000376671) (PubMed=11992403).
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-07-20; Version: 12
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RA   Carey T.E.;
RT   "Head and neck tumor cell lines.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994).
RX   PubMed=3360658; DOI=10.1016/0360-3016(88)90013-2;
RA   Weichselbaum R.R., Beckett M.A., Dahlberg W., Dritschilo A.;
RT   "Heterogeneity of radiation response of a parent human epidermoid
RT   carcinoma cell line and four clones.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 14:907-912(1988).
RX   PubMed=7214336;
RA   Rheinwald J.G., Beckett M.A.;
RT   "Tumorigenic keratinocyte lines requiring anchorage and fibroblast
RT   support cultured from human squamous cell carcinomas.";
RL   Cancer Res. 41:1657-1663(1981).
RX   PubMed=11992403; DOI=10.1002/ijc.10321;
RA   Popp S., Waltering S., Herbst C., Moll I., Boukamp P.;
RT   "UV-B-type mutations and chromosomal imbalances indicate common
RT   pathways for the development of Merkel and skin squamous cell
RT   carcinomas.";
RL   Int. J. Cancer 99:352-360(2002).
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).