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Cellosaurus SCC-12F (CVCL_4028)

[Text version]
Cell line name SCC-12F
Synonyms SCC 12F; SCC 12-F; SCC12F; SSC12f
Accession CVCL_4028
Resource Identification Initiative To cite this cell line use: SCC-12F (RRID:CVCL_4028)
Comments Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Leu; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Val216Gly (c.647T>G); ClinVar=VCV000376671; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4026 (SCC-12)
Children:
CVCL_M673 (SCC-12F.2)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=9204953; DOI=10.1111/1523-1747.ep12276459
Whitlow M.B., Klein L.M.
Response of SCC-12F, a human squamous cell carcinoma cell line, to complement attack.
J. Invest. Dermatol. 109:39-45(1997)

PubMed=22006338; DOI=10.1073/pnas.1114669108
Wang N.J., Sanborn Z., Arnett K.L., Bayston L.J., Liao W., Proby C.M., Leigh I.M., Collisson E.A., Gordon P.B., Jakkula L.R., Pennypacker S., Zou Y., Sharma M., North J.P., Vemula S.S., Mauro T.M., Neuhaus I.M., LeBoit P.E., Hur J.S., Park K., Huh N., Kwok P.-Y., Arron S.T., Massion P.P., Bale A.E., Haussler D., Cleaver J.E., Gray J.W., Spellman P.T., South A.P., Aster J.C., Blacklow S.C., Cho R.J.
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Proc. Natl. Acad. Sci. U.S.A. 108:17761-17766(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4028
Encyclopedic resources Wikidata; Q54952330
Polymorphism and mutation databases Cosmic; 1608863
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number13