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Cellosaurus SCC-13 (CVCL_4029)

[Text version]
Cell line name SCC-13
Synonyms SCC 13; SCC13
Accession CVCL_4029
Resource Identification Initiative To cite this cell line use: SCC-13 (RRID:CVCL_4029)
Comments Doubling time: 1 day (PubMed=34435183).
Omics: Deep quantitative proteome analysis.
Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
Sequence variations
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D2XN (SCC13-MET-KOc1-5)CVCL_D2XP (SCC13-MET-KOc1-8)CVCL_D2XQ (SCC13-MET-KOc4-2)
CVCL_D2XR (SCC13-MET-KOc4-3)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=7214336
Rheinwald J.G., Beckett M.A.
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas.
Cancer Res. 41:1657-1663(1981)

PubMed=6722007; DOI=10.1038/bjc.1984.94
Weichselbaum R.R., Dahlberg W.K., Little J.B., Ervin T.J., Miller D., Hellman S., Rheinwald J.G.
Cellular X-ray repair parameters of early passage squamous cell carcinoma lines derived from patients with known responses to radiotherapy.
Br. J. Cancer 49:595-601(1984)

PubMed=3458227; DOI=10.1073/pnas.83.8.2684
Weichselbaum R.R., Dahlberg W.K., Beckett M.A., Karrison T., Miller D., Clark J., Ervin T.J.
Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.
Proc. Natl. Acad. Sci. U.S.A. 83:2684-2688(1986)

PubMed=3417487; DOI=10.1016/0360-3016(88)90297-0
Weichselbaum R.R., Beckett M.A., Schwartz J.L., Dritschilo A.
Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy.
Int. J. Radiat. Oncol. Biol. Phys. 15:575-579(1988)

PubMed=2573646; DOI=10.1080/09553008914551731
Weichselbaum R.R., Rotmensch J., Ahmed-Swan S., Beckett M.A.
Radiobiological characterization of 53 human tumor cell lines.
Int. J. Radiat. Biol. 56:553-560(1989)

PubMed=8390283; DOI=10.1038/bjc.1993.238
Burns J.E., Baird M.C., Clark L.J., Burns P.A., Edington K.G., Chapman C., Mitchell R., Robertson G., Soutar D., Parkinson E.K.
Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines.
Br. J. Cancer 67:1274-1284(1993)

DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994)

PubMed=11992403; DOI=10.1002/ijc.10321
Popp S., Waltering S., Herbst C., Moll I., Boukamp P.
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas.
Int. J. Cancer 99:352-360(2002)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=22546478; DOI=10.1016/j.ajpath.2012.02.028
Degen M., Natarajan E., Barron P., Widlund H.R., Rheinwald J.G.
MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin gamma2 expression in oral dysplasia and squamous cell carcinoma.
Am. J. Pathol. 180:2462-2478(2012)

PubMed=22564525; DOI=10.1158/0008-5472.CAN-12-0423
Goldie S.J., Mulder K.W., Tan D.W.-M., Lyons S.K., Sims A.H., Watt F.M.
FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.
Cancer Res. 72:3424-3436(2012)

PubMed=34435183; DOI=10.1016/j.mbplus.2021.100066
Vu B., Souza G.R., Dengjel J.
Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome.
Matrix Biol. Plus. 11:100066.1-100066.9(2021)

PubMed=34593609; DOI=10.1158/1541-7786.MCR-21-0306
Chen X., Adhikary G., Shrestha S., Xu W., Keillor J.W., Naselsky W., Eckert R.L.
Transglutaminase 2 maintains hepatocyte growth factor signaling to enhance the cancer cell phenotype.
Mol. Cancer Res. 19:2026-2035(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4029
IGRhCellID; SCC13%20GSE9585
TOKU-E; 3610
Anatomy/cell type resources BTO; BTO:0002193
CRISP screens repositories BioGRID_ORCS_Cell_line; 1574
Encyclopedic resources Wikidata; Q54952336
Polymorphism and mutation databases Cosmic; 740990
IARC_TP53; 1911
Proteomic databases PRIDE; PXD023701
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number21