Cellosaurus T3M-4 (CVCL_4056)

Cell line name T3M-4
Synonyms T3M4; Panc89; Panc-89; PANC-89; Panc 89
Accession CVCL_4056
Resource Identification Initiative To cite this cell line use: T3M-4 (RRID:CVCL_4056)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: KuDOS 95 cell line panel.
Sequence variation: TP53 p.Tyr220Cys (PubMed=11787853).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX
CSF1PO10
D13S31710,13
D16S53911,12
D5S81811
D7S82012
TH019.3
TPOX11,12
vWA18,19,21
Web pages http://www.pawefish.path.cam.ac.uk/PancCellLineDescriptions/T3M-4.html
Publications

PubMed=6821838; DOI=10.1002/1097-0142(19830215)51:4<662::AID-CNCR2820510419>3.0.CO;2-X
Okabe T., Yamaguchi N., Ohsawa N.
Establishment and characterization of a carcinoembryonic antigen (CEA)-producing cell line from a human carcinoma of the exocrine pancreas.
Cancer 51:662-668(1983)

PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C
Sirivatanauksorn V., Sirivatanauksorn Y., Gorman P.A., Davidson J.M., Sheer D., Moore P.S., Scarpa A., Edwards P.A.W., Lemoine N.R.
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
Int. J. Cancer 91:350-358(2001)

PubMed=11787853; DOI=10.1007/s004280100474
Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr M., Scarpa A.
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12692724; DOI=10.1007/s00428-003-0784-4
Sipos B., Moser S., Kalthoff H., Torok V., Lohr M., Kloppel G.
A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform.
Virchows Arch. 442:444-452(2003)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections RCB; RCB1021
Cell line databases/resources CCLE; T3M4_PANCREAS
Ontologies BTO; BTO:0002864
CLO; CLO_0050113
EFO; EFO_0002714
Biological sample resources BioSample; SAMN03472207
Gene expression databases GEO; GSM887684
GEO; GSM888776
GEO; GSM1374814
GEO; GSM1374815
GEO; GSM1374816
Polymorphism and mutation databases Cosmic; 710873
Cosmic; 724641
Cosmic; 736281
Cosmic; 922257
Cosmic; 922263
Cosmic; 933528
Cosmic; 2546061
Cosmic; 2546062