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Cellosaurus 4647 (CVCL_4075)

Cell line name 4647
Synonyms Continuous kidney cell line No. 4647
Accession CVCL_4075
Resource Identification Initiative To cite this cell line use: 4647 (RRID:CVCL_4075)
Comments Group: Non-human primate cell line.
Group: Vaccine production cell line.
Virology: Susceptible to infection by poliovirus type 1, type 2 and type 3 (PubMed=28046048).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534)
Sex of cell Sex unspecified
Age at sampling Adult
Category Spontaneously immortalized cell line

Mironova L.L., Kurbatov A.V., Grachev V.P., Kuznetsova N.V., Stobetskii V.I.
Continuous kidney cell line No. 4647 from an adult green monkey and its use in virological practice.
Vopr. Virusol. 29:503-506(1984)

Mironova L.L., Shalunova N.V., Lomanova G.A., Nikolaeva M.A., Khapchaev I.K.
Characteristics of a bank of the heteroploid kidney cell line 4647 from the green monkey.
Vopr. Virusol. 32:740-743(1987)

Isaenko A.A., Nemtsov I.V., Tsareva A.A.
A karyotype study of the cells of the African green monkey kidney cell line 4647 cultured long term in media with different sera.
Tsitologiia 32:736-740(1990)

Skarnovich M.O., Radaeva I.F., Vdovichenko G.V., Nechaeva E.A., Sergeev A.A., Petrishchenko V.A., Pliasunov I.V., Shishkina L.N., Ternovoi V.A., Smetannikova M.A., Agafonov A.P., Sergeev A.N.
4647-cell culture for preparation of recombinant bivaccine against smallpox and hepatitis B.
Vopr. Virusol. 52:37-40(2007)

PubMed=28046048; DOI=10.1371/journal.pone.0169391
Dotti S., Lombardo T., Villa R., Cacciamali A., Zanotti C., Andreani N.A., Cinotti S., Ferrari M.
Transformation and tumorigenicity testing of simian cell lines and evaluation of poliovirus replication.
PLoS ONE 12:E0169391-E0169391(2017)

Cell line collections (Providers) ECACC; 90091902
Cell line databases/resources CLO; CLO_0001013
CLDB; cl97
CLDB; cl98
Encyclopedic resources Wikidata; Q54603226
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number15