ID   4647
AC   CVCL_4075
SY   Continuous kidney cell line No. 4647
DR   CLO; CLO_0001013
DR   CLDB; cl97
DR   CLDB; cl98
DR   ECACC; 90091902
DR   IZSLER; BS CL 223
DR   Wikidata; Q54603226
RX   PubMed=2175469;
RX   PubMed=3445593;
RX   PubMed=6495709;
RX   PubMed=17500238;
RX   PubMed=28046048;
CC   Group: Non-human primate cell line.
CC   Group: Vaccine production cell line.
CC   Virology: Susceptible to infection by poliovirus type 1, type 2 and type 3 (PubMed=28046048).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9534; ! Chlorocebus aethiops (Green monkey)
SX   Sex unspecified
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 15
//
RX   PubMed=2175469;
RA   Isaenko A.A., Nemtsov I.V., Tsareva A.A.;
RT   "A karyotype study of the cells of the African green monkey kidney
RT   cell line 4647 cultured long term in media with different sera.";
RL   Tsitologiia 32:736-740(1990).
//
RX   PubMed=3445593;
RA   Mironova L.L., Shalunova N.V., Lomanova G.A., Nikolaeva M.A.,
RA   Khapchaev I.K.;
RT   "Characteristics of a bank of the heteroploid kidney cell line 4647
RT   from the green monkey.";
RL   Vopr. Virusol. 32:740-743(1987).
//
RX   PubMed=6495709;
RA   Mironova L.L., Kurbatov A.V., Grachev V.P., Kuznetsova N.V.,
RA   Stobetskii V.I.;
RT   "Continuous kidney cell line No. 4647 from an adult green monkey and
RT   its use in virological practice.";
RL   Vopr. Virusol. 29:503-506(1984).
//
RX   PubMed=17500238;
RA   Skarnovich M.O., Radaeva I.F., Vdovichenko G.V., Nechaeva E.A.,
RA   Sergeev A.A., Petrishchenko V.A., Pliasunov I.V., Shishkina L.N.,
RA   Ternovoi V.A., Smetannikova M.A., Agafonov A.P., Sergeev A.N.;
RT   "4647-cell culture for preparation of recombinant bivaccine against
RT   smallpox and hepatitis B.";
RL   Vopr. Virusol. 52:37-40(2007).
//
RX   PubMed=28046048; DOI=10.1371/journal.pone.0169391;
RA   Dotti S., Lombardo T., Villa R., Cacciamali A., Zanotti C.,
RA   Andreani N.A., Cinotti S., Ferrari M.;
RT   "Transformation and tumorigenicity testing of simian cell lines and
RT   evaluation of poliovirus replication.";
RL   PLoS ONE 12:E0169391-E0169391(2017).
//