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Cellosaurus DBS-FRhL-2 (CVCL_4160)

[Text version]

Cell line name DBS-FRhL-2
Synonyms DBS-FRHL-2; DBSFRhL-2; DBSFRHL-2; DBSFRhL2; FRhL-2; FrHL-2; FrhL2; Division of Biologics Standards-Fetal Rhesus Lung-2
Accession CVCL_4160
Resource Identification Initiative To cite this cell line use: DBS-FRhL-2 (RRID:CVCL_4160)
Comments Group: Non-human primate cell line.
Group: Vaccine production cell line.
Biotechnology: Was used from 1997 to 1999 for the production of the rhesus rotavirus vaccine-tetravalent (RRV-TV) by Wyeth Laboratories (Trade Name: RotaShield).
Characteristics: Senesces at ~74 PDL.
Discontinued: IZSLER; BS CL 215; probable.
Derived from sampling site: Fetal lung.
Species of origin Macaca mulatta (Rhesus macaque) (NCBI Taxonomy: 9544)
Sex of cell Male
Age at sampling Fetus
Category Finite cell line
Publications

PubMed=4348695; DOI=10.1007/BF02619056
Wallace R.E., Vasington P.J., Petricciani J.C., Hopps H.E., Lorenz D.E., Kadanka Z.
Development of a diploid cell line from fetal rhesus monkey lung for virus vaccine production.
In Vitro 8:323-332(1973)

PubMed=4203458
Petricciani J.C., Wallace R.E., McCoy D.W.
A comparison of three in vivo assays for cell tumorigenicity.
Cancer Res. 34:105-108(1974)

Patent=US4040905
Hopps H.E., Lorenz D.E., Petricciani J.C., Vasington P.J., Wallace R.E.
Sub-human primate diploid cell lines as substrates for virus vaccine production.
Patent number US4040905, 09-Aug-1977

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

Cross-references
Cell line collections ATCC; CL-160
ATCC; CCL-160 - Discontinued
ECACC; 89101303
IZSLER; BS CL 215
Cell line databases/resources CLDB; cl1004
Ontologies CLO; CLO_0002721
Other Wikidata; Q54828612
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number13