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Cellosaurus Do-11-10 (CVCL_4163)

Cell line name Do-11-10
Synonyms DO-11.10; DO 11.10; Do11.10; DO11.10
Accession CVCL_4163
Resource Identification Initiative To cite this cell line use: Do-11-10 (RRID:CVCL_4163)
Comments Characteristics: T-cell hybridoma originally elicited by vaccination of BALB/c mice (H-2d haplotype) with chicken ovalbumin. Popular model system to study CD4+ T cell responses.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3896 (BW5147)
Children:
CVCL_U810 (DMyc3-45)CVCL_U811 (DMyc9-36)CVCL_WK48 (Do-11-10 mutant 51)
Category Hybridoma
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/d/cell-lines-detail-77.html
Publications

PubMed=6185566; DOI=10.4049/jimmunol.130.3.1033
White J., Haskins K.M., Marrack P., Kappler J.W.
Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies.
J. Immunol. 130:1033-1037(1983)

PubMed=10200546; DOI=10.1038/sj.cdd.4400447
Morgan G., Smith S., Pak J., Marshak-Rothstein A., Fissore R., Osborne B.
Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway.
Cell Death Differ. 6:36-47(1999)

PubMed=10590261; DOI=10.1093/intimm/11.12.1957
Takemoto Y., Furuta M., Sato M., Kubo M., Hashimoto Y.
Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3.
Int. Immunol. 11:1957-1964(1999)

PubMed=23110081; DOI=10.1371/journal.pone.0047585
Roy B.M., Zhukov D.V., Maynard J.A.
Flanking residues are central to DO11.10 T cell hybridoma stimulation by ovalbumin 323-339.
PLoS ONE 7:E47585-E47585(2012)

Cross-references
Cell line collections (Providers) ECACC; 85082301
Cell line databases/resources Lonza; 881
TOKU-E; 4126
Anatomy/cell type resources BTO; BTO:0004333
Encyclopedic resources Wikidata; Q54831338
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number12